Cad Saude Publica. 2014 Mar;30(3):559-66. doi: 10.1590/0102-311x00005813.
The aim of this study was to analyze prostate cancer mortality and time trends in Brazil, according to major geographic regions, States, and age brackets. Data on deaths from 1980 to 2010 were obtained from the Mortality Information System. Mortality trends were estimated using Prais-Winsten generalized linear regression. An upward time trend was observed in mortality in all regions of Brazil, with a mean annual increase of 2.8%. The upward trend in mortality occurred in most of the age brackets, with a concentration of deaths in men 70 to 79 years of age (41%) and a significant increase in the 40 to 60-year age bracket. The mortality rate increased significantly in all age brackets in the Northeast, compared to the other regions of Brazil. The study highlighted the importance of redistributing deaths from ill-defined causes in order to correct the mortality rates. The results point to significant regional differences and the need for continuous monitoring of mortality from prostate cancer in Brazil.
本研究旨在分析巴西各主要地理区域、州和年龄组的前列腺癌死亡率和时间趋势。1980 年至 2010 年的死亡数据来自死亡信息系统。使用普赖斯-温斯坦广义线性回归法估计死亡率趋势。巴西所有地区的死亡率均呈上升趋势，平均年增长率为 2.8%。死亡率上升趋势发生在大多数年龄组中，70 至 79 岁男性的死亡人数（41%）集中，40 至 60 岁年龄组的死亡率显著增加。与巴西其他地区相比，东北地区所有年龄组的死亡率均显著增加。本研究强调了重新分配不明原因死亡的重要性，以纠正死亡率。结果表明存在显著的地区差异，需要对巴西前列腺癌的死亡率进行持续监测。
