Moura Alex Rodrigues, Marques Adriane Dórea, Dantas Mylena Santos, de Abreu Costa Brito Érika, do Rosário Souza Mariana, Lima Marcela Sampaio, Siqueira Hianga Fayssa Fernandes, da Silva Angela Maria, Lisboa Ana Carolina Ribeiro, Nunes Marco Antonio Prado, de Oliveira Santos Marceli, Lima Carlos Anselmo
Health Sciences Graduate Program, Aracaju, Sergipe, Brazil.
University Hospital, EBSERH/Federal University of Sergipe, Aracaju, Sergipe, Brazil.
BMC Res Notes. 2020 Dec 9;13(1):560. doi: 10.1186/s13104-020-05411-9.
This study was conducted to analyze the trends in colorectal cancer (CRC) incidence and mortality in the city of Aracaju, Sergipe State, Brazil, between 1996 and 2015 with Joinpoint Regression Program 4.7.0.0 and to identify the geographical distribution of CRC in the municipality.
A total of 1322 cases of CRC and 467 CRC-related deaths during the study period were included. In total, 40% of the incident cases and 43% of the deaths occurred in men, while 60% of the incident cases and 57% of the deaths occurred in women. Males who were 20 to 44 years old had the most significant trend in growth. Among women, those in the group aged 45 to 64 years had the highest observed annual percent change (APC). In both sexes, mortality was stable. Regarding the geographic distribution, there were constant hotspots in the northeast region of the municipality. This study showed a significant increase in incidence, mainly in young men between 20 and 44 years of age, but stable mortality in Aracaju.
本研究旨在使用Joinpoint回归程序4.7.0.0分析1996年至2015年巴西塞尔希培州阿拉卡茹市结直肠癌（CRC）的发病率和死亡率趋势，并确定该市CRC的地理分布。
研究期间共纳入1322例CRC病例和467例与CRC相关的死亡病例。总体而言，40%的发病病例和43%的死亡病例发生在男性，而60%的发病病例和57%的死亡病例发生在女性。20至44岁的男性增长趋势最为显著。在女性中，45至64岁年龄组的观察到的年变化百分比（APC）最高。在两性中，死亡率稳定。关于地理分布，该市东北部地区存在持续的热点地区。本研究表明，阿拉卡茹市的发病率显著增加，主要是在20至44岁的年轻男性中，但死亡率稳定。
