• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

中枢神经系统疾病，由机会性和合并感染引起。

Central nervous system diseases due to opportunistic and coinfections.

机构信息

Department of Neurology, Harborview Medical Center, Seattle, Washington.

出版信息

Semin Neurol. 2014 Feb;34(1):61-9. doi: 10.1055/s-0034-1372343. Epub 2014 Apr 8.

DOI:10.1055/s-0034-1372343
PMID:24715489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10981391/
Abstract

With the widespread use of combination antiretroviral therapy (cART), the incidence of central nervous system (CNS) opportunistic infections and coinfections has significantly decreased. This review focuses on the clinical presentation, diagnostic laboratory and radiologic findings, as well as the treatment of neurosyphilis, progressive multifocal leukoencephalopathy, primary CNS lymphoma, and toxoplasmosis, which are CNS opportunistic infections and coinfections that are most relevant to clinicians in North America.

摘要

随着联合抗逆转录病毒疗法（cART）的广泛应用，中枢神经系统（CNS）机会性感染和合并感染的发病率显著下降。本文重点介绍了与北美临床医生最相关的几种 CNS 机会性感染和合并感染，包括神经梅毒、进行性多灶性白质脑病、原发性中枢神经系统淋巴瘤和弓形虫病的临床特征、诊断实验室和影像学表现，以及治疗方法。

相似文献

1
Central nervous system diseases due to opportunistic and coinfections.中枢神经系统疾病，由机会性和合并感染引起。
Semin Neurol. 2014 Feb;34(1):61-9. doi: 10.1055/s-0034-1372343. Epub 2014 Apr 8.
2
[Infections of the central nervous system in immunodeficiency].[免疫缺陷状态下的中枢神经系统感染]
Internist (Berl). 2019 Jul;60(7):690-700. doi: 10.1007/s00108-019-0614-7.
3
Central nervous system opportunistic infections in developed countries in the highly active antiretroviral therapy era.高效抗逆转录病毒治疗时代发达国家的中枢神经系统机会性感染
J Neurovirol. 2005;11 Suppl 3:72-82. doi: 10.1080/13550280500513846.
4
[AIDS and opportunistic infections of the central nervous system].
Acta Neurol (Napoli). 1989 Apr-Jun;11(2-3):117-26.
5
Opportunistic Neurologic Infections in Patients with Acquired Immunodeficiency Syndrome (AIDS).获得性免疫缺陷综合征（艾滋病）患者的机会性神经系统感染。
Curr Neurol Neurosci Rep. 2016 Jan;16(1):10. doi: 10.1007/s11910-015-0603-8.
6
Central nervous system dysfunction in acquired immunodeficiency syndrome.获得性免疫缺陷综合征中的中枢神经系统功能障碍
J Acquir Immune Defic Syndr (1988). 1988;1(1):41-64.
7
[Opportunistic infections of the central nervous system in patients with AIDS].[艾滋病患者中枢神经系统的机会性感染]
Arch Neurobiol (Madr). 1989;52 Suppl 1:108-20.
8
Opportunistic infections of the central nervous system in the transplant patient.移植患者中枢神经系统机会性感染。
Curr Neurol Neurosci Rep. 2013 Sep;13(9):376. doi: 10.1007/s11910-013-0376-x.
9
How AIDS attacks the brain.
Am J Nurs. 1990 Jan;90(1):44-52.
10
Central nervous system disorders in AIDS.艾滋病中的中枢神经系统疾病
Immunol Ser. 1989;44:371-401.

引用本文的文献

1
Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress.纳米制剂抗逆转录病毒疗法可减轻大脑代谢性氧化应激。
Mol Neurobiol. 2019 Apr;56(4):2896-2907. doi: 10.1007/s12035-018-1273-8. Epub 2018 Aug 1.
2
Anti-N-methyl-D-aspartate receptor encephalitis associated with acute Toxoplasma gondii infection: A case report.与急性弓形虫感染相关的抗N-甲基-D-天冬氨酸受体脑炎：一例报告。
Medicine (Baltimore). 2018 Feb;97(7):e9924. doi: 10.1097/MD.0000000000009924.
3
A 27-Year-Old Man With Right-Sided Hemiparesis and Dysarthria.一名27岁右侧偏瘫及构音障碍男性患者。
Neurohospitalist. 2016 Oct;6(4):174-180. doi: 10.1177/1941874416648197. Epub 2016 May 11.

本文引用的文献

1
In situ evidence of JC virus control by CD8+ T cells in PML-IRIS during HIV infection.在 HIV 感染期间 PML-IRIS 中 CD8+ T 细胞对 JC 病毒的控制的原位证据。
Neurology. 2013 Sep 10;81(11):964-70. doi: 10.1212/WNL.0b013e3182a43e6d. Epub 2013 Aug 9.
2
A study of mefloquine treatment for progressive multifocal leukoencephalopathy: results and exploration of predictors of PML outcomes.一项关于甲氟喹治疗进行性多灶性白质脑病的研究：结果及对 PML 结局预测因素的探索。
J Neurovirol. 2013 Aug;19(4):351-8. doi: 10.1007/s13365-013-0173-y. Epub 2013 Jun 4.
3
PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section.PML 诊断标准：美国神经病学学会神经感染疾病分会的共识声明。
Neurology. 2013 Apr 9;80(15):1430-8. doi: 10.1212/WNL.0b013e31828c2fa1.
4
Immune reconstitution inflammatory syndrome involving the central nervous system in a patient with HIV infection: a case report and review of literature.一名HIV感染患者发生的累及中枢神经系统的免疫重建炎症综合征：病例报告及文献复习
New Microbiol. 2013 Jan;36(1):89-92. Epub 2013 Jan 1.
5
Evaluation of progressive multifocal leukoencephalopathy treatments in a Spanish cohort of HIV-infected patients: do protease inhibitors improve survival regardless of central nervous system penetration-effectiveness (CPE) score?评估西班牙 HIV 感染患者中进行性多灶性白质脑病的治疗方法：蛋白酶抑制剂是否不论中枢神经系统穿透效果（CPE）评分如何都能改善生存？
HIV Med. 2013 May;14(5):321-5. doi: 10.1111/hiv.12008. Epub 2012 Dec 6.
6
Increasing trends of gonorrhoea and syphilis and the threat of drug-resistant gonorrhoea in Europe.欧洲淋病和梅毒发病率呈上升趋势以及耐药性淋病带来的威胁。
Euro Surveill. 2012 Jul 19;17(29):20225.
7
Syphilis and neurosyphilis in human immunodeficiency virus-infected patients: a retrospective study at a teaching hospital in Taiwan.梅毒和 HIV 感染者的神经梅毒：台湾一家教学医院的回顾性研究。
J Microbiol Immunol Infect. 2012 Oct;45(5):337-42. doi: 10.1016/j.jmii.2011.12.011. Epub 2012 Jun 13.
8
The rapid plasma reagin test cannot replace the venereal disease research laboratory test for neurosyphilis diagnosis.快速血浆反应素试验不能替代性病研究实验室试验用于神经梅毒的诊断。
Sex Transm Dis. 2012 Jun;39(6):453-7. doi: 10.1097/OLQ.0b013e31824b1cde.
9
Atypical progressive multifocal leukoencephalopathy in HIV with a high CD4 count: the use of magnetic resonance imaging plus spectrometry studies.CD4计数高的HIV患者中的非典型进行性多灶性白质脑病：磁共振成像联合光谱分析研究的应用
Int J STD AIDS. 2012 Mar;23(3):e35-8. doi: 10.1258/ijsa.2009.009136.
10
JC virus-associated central nervous system diseases in HIV-infected patients in Brazil: clinical presentations, associated factors with mortality and outcome.巴西 HIV 感染患者中与 JC 病毒相关的中枢神经系统疾病：临床表现、与死亡率相关的因素及预后。
Braz J Infect Dis. 2012 Mar-Apr;16(2):153-6.