Gupta Sangeeta
Del Med J. 2014 Jan;86(1):13-20.
The purpose of this study is to determine the relative associations of obesity with the prevalence of diabetes and diabetes-related cardiovascular comorbidities in Delaware. Compelling research evidence demonstrates that obesity is a major independent risk factor both for diabetes and cardiovascular disease.
Analysis was conducted using Delaware data for 4,777 respondents from the 2011 Behavioral Risk Factor Surveillance System (BRFSS).
The likelihood of having diabetes and diabetes-related cardiovascular (CVD) comorbidities increased with Body Mass Index (BMI). Compared with normal-weight adults, the multivariate-adjusted odds ratio (OR) for diabetes was 7.14 (95 percent confidence interval [CI] 4.70-10.83) and 2.54 (95 percent CI, 1.65-3.92); OR for diabetes and comorbid hypertension was 9.93 (95 percent CI, 5.82-16.93) and 3.66 (95 percent CI 2.13-6.30); OR for diabetes and high cholesterol OR was 6.76 (95 percent CI, 3.98-11.48) and 3.09 (95 percent CI,1.78-5.37); and the OR for diabetes and heart disease was 7.64 (95 percent CI, 3.15-18.50) and 3.82 (95 percent CI, 1.42-10.30) in obese and overweight adult Delawareans, respectively.
One of the objectives of Healthy People 2020 is to reduce the rate of cardiovascular disease deaths in persons with diagnosed diabetes. Findings from this study provide compelling local data for health professionals to prioritize and implement evidence based obesity prevention and control interventions among persons with diagnosed diabetes to reduce the risk of cardiovascular comorbidities.
本研究旨在确定在特拉华州肥胖与糖尿病患病率及糖尿病相关心血管合并症之间的相对关联。有力的研究证据表明,肥胖是糖尿病和心血管疾病的主要独立危险因素。
使用来自2011年行为危险因素监测系统(BRFSS)的4777名特拉华州受访者的数据进行分析。
患糖尿病及糖尿病相关心血管(CVD)合并症的可能性随体重指数(BMI)升高而增加。与体重正常的成年人相比,肥胖和超重的特拉华州成年人患糖尿病的多变量调整优势比(OR)分别为7.14(95%置信区间[CI]4.70 - 10.83)和2.54(95%CI,1.65 - 3.92);患糖尿病合并高血压的OR分别为9.93(95%CI,5.82 - 16.93)和3.66(95%CI 2.13 - 6.30);患糖尿病合并高胆固醇的OR分别为6.76(95%CI,3.98 - 11.48)和3.09(95%CI,1.78 - 5.37);患糖尿病合并心脏病的OR分别为7.64(95%CI,3.15 - 18.50)和3.8C(95%CI,1.42 - 10.30)。
《健康人民2020》的目标之一是降低已确诊糖尿病患者的心血管疾病死亡率。本研究结果为卫生专业人员提供了有力的本地数据,以便他们在已确诊糖尿病患者中优先开展并实施基于证据的肥胖预防和控制干预措施,以降低心血管合并症的风险。