Kapoor Aditya, Jain Rajat, Sahu Srikant, Sangwan Virender
Cornea Services, L V Prasad Eye Institute, Bhubaneshwar, Odisha, India.
BMJ Case Rep. 2014 Mar 7;2014:bcr2013202200. doi: 10.1136/bcr-2013-202200.
A 44-year-old man presented with severe pain, redness, watering and photophobia for 10 days in the right eye without any history of trauma. Diagnosis of herpes simplex disciform keratitis was made and he was prescribed topical steroids. The patient showed clinical worsening and presented with ring infiltrate, diffuse stromal oedema and radial keratoneuritis, a finding pathognomic of acanthamoeba keratitis. With two inconclusive corneal scrapings and the patient showing clinical worsening, an urgent therapeutic penetrating keratoplasty was carried out. Histopathological and microbiological examination of the excised corneal button revealed the presence of fungus. At 5 weeks follow-up, the patient has best-corrected visual acuity 20/40 with no recurrence of infection.
一名44岁男性,右眼出现严重疼痛、发红、流泪及畏光10天,无任何外伤史。诊断为单纯疱疹性盘状角膜炎,并给他开了局部类固醇药物。患者病情临床恶化,出现环形浸润、弥漫性基质水肿和放射状角膜神经炎,这是棘阿米巴角膜炎的典型表现。由于两次角膜刮片结果均不确定且患者临床症状恶化,遂紧急进行了治疗性穿透性角膜移植术。对切除的角膜植片进行组织病理学和微生物学检查发现有真菌存在。在5周的随访中,患者最佳矫正视力为20/40,感染无复发。