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[肥胖——男性勃起功能障碍的重要风险因素]

[Obesity--significant risk factor for erectile dysfunction in men].

作者信息

Skrypnik Damian, Bogdański Paweł, Musialik Katarzyna

出版信息

Pol Merkur Lekarski. 2014 Feb;36(212):137-41.

PMID:24720114
Abstract

The obesity affects around 312 million people over the world. In The United States it causes more than 300 000 deaths per year. It leads to many complications, such as ischemic heart disease, hypertension, dyslipidemia, atherosclerosis and abnormal carbohydrate metabolism. It was proven recently that obesity is also an independent risk factor for erectile dysfunction in men. 79% of men presenting erectile disorders have BMI of 25 kg/m2 or greater. BMI in the range 25-30 kg/m2 is associated with 1,5 times, and in the range of over 30 kg/m2 with 3 times greater risk of sexual dysfunction. The occurrence of erectile dysfunction in patients with obesity is caused by a number of complications which are characteristic for an excessive amount of fat tissue, in example: cardiovascular diseases, diabetes or dyslipidemia. In the United States diabetes and obesity are responsible for 8 million cases of erectile dysfunction. Scientific evidence indicates that excessive body weight should be considered as an independent risk factor for erectile dysfunction. This risk increases with increasing BMI. Erectile disorders correlate with the occurrence of obesity at any time during the patient's life. Obesity leads to erectile dysfunction in a considerably greater extent than aging. Mechanisms responsible for the independent influence of obesity on the erectile dysfunction are: hormonal imbalance, endothelial dysfunction, insulin resistance, psychological factors and physical inactivity. The basis for erectile dysfunction treatment in obesity is body weight loss. Erectile disorders in obese men are significantly more frequent than in general population. Obesity is beyond any doubts an independent risk factor of erectile dysfunction.

摘要

肥胖影响着全球约3.12亿人。在美国,肥胖每年导致超过30万人死亡。它会引发许多并发症,如缺血性心脏病、高血压、血脂异常、动脉粥样硬化和碳水化合物代谢异常。最近有证据表明,肥胖也是男性勃起功能障碍的一个独立危险因素。出现勃起功能障碍的男性中,79%的人体重指数(BMI)为25千克/平方米或更高。BMI在25至30千克/平方米之间的男性出现性功能障碍的风险是正常人的1.5倍,而BMI超过30千克/平方米的男性这一风险则高达3倍。肥胖患者出现勃起功能障碍是由一些脂肪组织过多所特有的并发症引起的,比如心血管疾病、糖尿病或血脂异常。在美国,糖尿病和肥胖导致了800万例勃起功能障碍。科学证据表明,超重应被视为勃起功能障碍的一个独立危险因素。这种风险会随着BMI的增加而上升。勃起功能障碍在患者生命中的任何时候都与肥胖的发生相关。肥胖导致勃起功能障碍的程度比衰老要大得多。肥胖对勃起功能障碍产生独立影响的机制包括:激素失衡、内皮功能障碍、胰岛素抵抗、心理因素和缺乏运动。肥胖患者勃起功能障碍治疗的基础是减轻体重。肥胖男性出现勃起功能障碍的频率明显高于普通人群。毫无疑问,肥胖是勃起功能障碍的一个独立危险因素。

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