Dani K A, Warach S
From the Institute of Neurosciences and Psychology (K.A.D.), University of Glasgow, Institute of Neurological Sciences, Glasgow, United Kingdom.
Department of Neurology and Neurotherapeutics (S.W.), UT Southwestern, Dallas, Texas.
AJNR Am J Neuroradiol. 2014 Jun;35(6 Suppl):S37-43. doi: 10.3174/ajnr.A3789. Epub 2014 Apr 10.
Measures of cerebral metabolism may be useful in the selection of patients for reperfusion therapies and as end points in clinical trials. However, there are currently no clinically routine techniques that provide such data directly. We review how imaging modalities in current clinical use may provide surrogate markers of metabolic activity. Promising techniques for metabolic imaging that are currently in the pipeline are reviewed.
脑代谢测量对于选择接受再灌注治疗的患者以及作为临床试验的终点可能是有用的。然而,目前尚无直接提供此类数据的临床常规技术。我们回顾了当前临床使用的成像方式如何能够提供代谢活动的替代标志物。同时也对目前正在研发中的有前景的代谢成像技术进行了综述。