Conceição Cristiane Maria, Dornaus Maria Fernanda Pellegrino da Silva, Portella Maria Aparecida, Deutsch Alice D Agostini, Rebello Celso Moura
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Einstein (Sao Paulo). 2014 Jan-Mar;12(1):11-5. doi: 10.1590/s1679-45082014ao2711.
To investigate the influence of the site of measurement of transcutaneous bilirubin (forehead or sternum) in reproducibility of results as compared to plasma bilirubin.
A cohort study including 58 term newborns with no hemolytic disease. Transcutaneous measurements were performed on the forehead (halfway between the headline and the glabella, from the left toward the right side, making consecutive determinations, one-centimeter apart) and the sternum (five measurements, from the suprasternal notch to the xiphoid process with consecutive determinations, one-centimeter apart) using Bilicheck® (SpectRx Inc, Norcross, Georgia, USA). The correlation and agreement between both methods and plasma bilirubin were calculated.
There was a strong linear correlation between both determinations of serum bilirubin at the forehead and sternum (r=0.704; p<0.01 and r=0.653; p<0.01, respectively). There was correspondence of the mean values of transcutaneous bilirubin measured on the sternum (9.9 ± 2.2mg/dL) compared to plasma levels (10.2 ± 1.7 mg/dL), but both differ from the values measured on the forehead (8.6 ± 2 .0mg/dL), p<0.05.
In newborn term infants with no hemolytic disease, measuring of transcutaneous bilirubin on the sternum had higher accuracy as compared to serum bilirubin measurement on the forehead.
与血浆胆红素相比,研究经皮胆红素测量部位(前额或胸骨)对结果可重复性的影响。
一项队列研究,纳入58例无溶血病的足月儿。使用Bilicheck®(美国佐治亚州诺克罗斯市SpectRx公司)在前额(发际线与眉间中点,从左至右,连续测定,间隔1厘米)和胸骨(5次测量,从胸骨上切迹至剑突,连续测定,间隔1厘米)进行经皮测量。计算两种方法与血浆胆红素之间的相关性和一致性。
前额和胸骨处血清胆红素的两次测定之间均存在强线性相关性(分别为r = 0.704;p < 0.01和r = 0.653;p < 0.01)。胸骨处经皮胆红素测量平均值(9.9±2.2mg/dL)与血浆水平(10.2±1.7mg/dL)相符,但两者均与前额测量值(8.6±2.0mg/dL)不同,p < 0.05。
在无溶血病的足月儿中,与前额血清胆红素测量相比,胸骨处经皮胆红素测量具有更高的准确性。