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乳腺钼靶密度与乳制品消费、阳光照射及日常活动的关联

Association of mammographic breast density with dairy product consumption, sun exposure, and daily activity.

作者信息

Alipour Sadaf, Saberi Azin, Alikhassi Afsaneh, Bayani Leila, Hosseini Ladan

机构信息

Surgery Department, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran ; Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Surgery Department, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

ISRN Oncol. 2014 Mar 4;2014:159049. doi: 10.1155/2014/159049. eCollection 2014.

Abstract

Background. Mammographic density is a risk factor, for breast cancer and its association with various factors is under investigation; we carried out a study to assess its relationship with daily dairy intake, sun exposure, and physical activities. Patients and Methods. Women ≥40 years of age were interviewed about habits of dairy product consumption, daily sun exposure and physical activity. Exclusion criteria consisted of history of breast cancer, consumption of calcium and vitamin D supplements, hormone replacement therapy, or renal disease. Mammographic densities were classified according to the classification system of the American College of Radiologists into 4 classes. Results. Overall 703 cases were entered in the study. The mean age was 48.2 ± 6.2 years. The most common and least frequent classes of mammographic density were classes 2 and 4, respectively. There was no significant association between mammographic density and rate of dairy consumption, amount of sunlight exposure, and daily physical activity. Conclusion. Relation of sunlight exposure and intake of milk products with mammographic density need further study, while the subject of physical activity can be evaluated by a systematic review and meta-analysis of the existing literature.

摘要

背景。乳腺钼靶密度是乳腺癌的一个风险因素,其与各种因素的关联正在研究中;我们开展了一项研究以评估其与日常乳制品摄入量、阳光照射及体育活动的关系。

患者与方法。对年龄≥40岁的女性就乳制品消费习惯、日常阳光照射及体育活动进行了访谈。排除标准包括乳腺癌病史、钙和维生素D补充剂的使用、激素替代疗法或肾病。根据美国放射学会的分类系统将乳腺钼靶密度分为4类。

结果。该研究共纳入703例病例。平均年龄为48.2±6.2岁。乳腺钼靶密度最常见和最不常见的类别分别为2类和4类。乳腺钼靶密度与乳制品消费率、阳光照射量及日常体育活动之间无显著关联。

结论。阳光照射及乳制品摄入与乳腺钼靶密度的关系需进一步研究,而体育活动这一主题可通过对现有文献进行系统评价和荟萃分析来评估。

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