Shu Xing-zhong, Zhang Miao, He Ying, Frei Heinz, Toste F Dean
Department of Chemistry, University of California , Berkeley, California 94720, United States.
J Am Chem Soc. 2014 Apr 23;136(16):5844-7. doi: 10.1021/ja500716j. Epub 2014 Apr 14.
A combination of visible light photocatalysis and gold catalysis is applied to a ring expansion-oxidative arylation reaction. The reaction provides an entry into functionalized cyclic ketones from the coupling reaction of alkenyl and allenyl cycloalkanols with aryl diazonium salts. A mechanism involving generation of an electrophilic gold(III)-aryl intermediate is proposed on the basis of mechanistic studies, including time-resolved FT-IR spectroscopy.
可见光光催化与金催化相结合应用于扩环-氧化芳基化反应。该反应通过烯基和联烯基环烷醇与芳基重氮盐的偶联反应，提供了一种合成官能化环酮的方法。基于包括时间分辨傅里叶变换红外光谱在内的机理研究，提出了一种涉及亲电金(III)-芳基中间体生成的机理。
