Farasat Massoumeh, Khavari-Nejad Ramazan-Ali, Nabavi Seyed Mohammad Bagher, Namjooyan Foroogh
Department of Biology , Science and Research Branch , Islamic Azad University,Tehran, Iran.
Department of Marine Biology, University of Marine Sciences and Technology, Khorramshahr, , Iran.
Iran J Pharm Res. 2014 Winter;13(1):163-70.
The antioxidant activity, contents of total phenolics and flavonoids were quantified in the methanolic extracts of four Ulva species (Ulva clathrata (Roth) C.Agardh, Ulva linza Linnaeus, Ulva flexuosa Wulfen and Ulva intestinalis Linnaeus) grown at different parts of northern coasts of the Persian Gulf in south of Iran. The seaweeds were collected from Dayyer, Taheri and Northern Ouli coasts in April 2011. Methanolic extracts of the seaweeds were assessed for their antioxidant activity using DPPH radical scavenging assay and was performed in a microplate reader. All species exhibited a DPPH radical scavenging activity, and among the species, Ulva clathrata demonstrated greater antioxidant potential with a low IC50 (0.881 mg mL(-1)) in comparison with those of the other species. Also the highest phenolic content (5.080 mg GAE g(-1)) and flavonoid content (33.094 mg RE g(-1)) were observed in U.clathrata. Total phenolic and flavonoid contents showed positive correlations with the DPPH radical scavenging activity (p < 0.01) and negative correlations with IC50 (p < 0.01).The results suggest that these edible green seaweeds possess antioxidant potential which could be considered for future applications in medicine, dietary supplements ,cosmetics or food industries.
对生长在伊朗南部波斯湾北部海岸不同区域的四种石莼属海藻（孔石莼（Roth）C.Agardh、条浒苔、肠浒苔和扁浒苔）的甲醇提取物中的抗氧化活性、总酚和黄酮含量进行了定量分析。这些海藻于2011年4月从代耶尔、塔赫里和乌利北部海岸采集。采用DPPH自由基清除法评估海藻甲醇提取物的抗氧化活性，并在酶标仪上进行检测。所有种类均表现出DPPH自由基清除活性，其中孔石莼与其他种类相比，具有较低的半数抑制浓度（IC50为0.881 mg mL(-1)），展现出更强的抗氧化潜力。此外，在孔石莼中还观察到最高的酚类含量（5.080 mg GAE g(-1)）和黄酮含量（33.094 mg RE g(-1)）。总酚和黄酮含量与DPPH自由基清除活性呈正相关（p < 0.01），与IC50呈负相关（p < 0.01）。结果表明，这些可食用绿藻具有抗氧化潜力，可考虑在医药、膳食补充剂、化妆品或食品工业中加以应用。
