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两种补铁方法对大不里士学生血红蛋白水平和月经出血量的比较。

Comparison of two iron supplementation methods on Hemoglobin level and Menstrual Bleeding in Tabriz students.

作者信息

Bani S, Hassanpour-Siahestalkhi A, Hassanpour Sh, Mommad-Alizadeh-Charandabi S, Mirghafourvand M, Javadzadeh Y

机构信息

Instructor, Department of Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

Student in Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Iran J Ped Hematol Oncol. 2014;4(1):11-6. Epub 2014 Feb 20.

Abstract

BACKGROUND

Iron deficiency anemia is a global health problem, and approximately 50% of anemia is caused by iron deficiency. According to studies, iron supplementation in young females improves iron status by increasing concentration of hemoglobin. To compare of prescribing two methods of iron supplementation administered either on a weekly basis or during menstruation, on hemoglobin level and menstrual blood¸ this double blind Randomized clinical trial study was carried out among female students in Tabriz, Iran.

MATERIALS AND METHODS

In this double-blind randomized clinical trial, 150 female students allocated randomly in two groups. (75 students took an iron tablet weekly and 75 students took an iron tablet for first four days during their menstruation cycle for 16 weeks). Before and after intervention, the level of hemoglobin was measured and Higham chart was completed by participants in each group. Chi-square, independent t-Test, paired t-Test and ANCOVA were used for data analysis.

RESULTS

There was no significant difference between two groups in terms of demographic characteristics, hemoglobin level and amount of menstrual bleeding before and after intervention (p>0.05). Taking iron supplement increased significantly the level of hemoglobin in each group (p<0.001). However, there was no significant difference in amount of menstrual bleeding (p>0.05) when comparing the data before and after intervention in each group.

CONCLUSION

The two iron supplementation methods (menstrual bleeding period and weekly) have similar results on Hemoglobin level and menstrual bleeding.

摘要

背景

缺铁性贫血是一个全球性的健康问题,约50%的贫血是由缺铁引起的。根据研究,年轻女性补充铁剂可通过提高血红蛋白浓度来改善铁状态。为比较每周补铁和经期补铁这两种补铁方法对血红蛋白水平和月经量的影响,在伊朗大不里士的女学生中开展了这项双盲随机临床试验研究。

材料与方法

在这项双盲随机临床试验中,150名女学生被随机分为两组。(75名学生每周服用一片铁剂,75名学生在月经周期的前四天每天服用一片铁剂,持续16周)。干预前后,测量血红蛋白水平,并由每组参与者完成海厄姆图表。采用卡方检验、独立样本t检验、配对t检验和协方差分析进行数据分析。

结果

两组在人口统计学特征、干预前后的血红蛋白水平和月经量方面均无显著差异(p>0.05)。补充铁剂显著提高了每组的血红蛋白水平(p<0.001)。然而,比较每组干预前后的数据时,月经量无显著差异(p>0.05)。

结论

两种补铁方法(经期补铁和每周补铁)对血红蛋白水平和月经量的影响相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d4/3980016/a992663defdd/ijpho-4-11-g001.jpg

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