Cameron Michelle H, Peterson Vanessa, Boudreau Eilis A, Downs Ashley, Lovera Jesus, Kim Edward, McMillan Garnett P, Turner Aaron P, Haselkorn Jodie K, Bourdette Dennis
Department of Neurology, School of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L226, Portland, OR 97239, USA ; Multiple Sclerosis Center of Excellence-West, Portland Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
Portland Lung Clinic, Adventist Medical Center, Portland, OR 97216, USA.
Mult Scler Int. 2014;2014:872732. doi: 10.1155/2014/872732. Epub 2014 Mar 5.
Background. Fatigue is the most common symptom in people with multiple sclerosis (MS). Poor sleep also occurs in this population. Objective. The objective of this study was to determine the relationship between fatigue and sleep quality in people with MS and cognitive impairment. Method. This cross-sectional study assessed relationships among fatigue, assessed with the Modified Fatigue Impact Scale (MFIS) and the Fatigue Severity Scale (FSS), sleep quality assessed with the Pittsburg Sleep Quality Index (PSQI), and demographics in 121 people with MS and cognitive impairment. Results. Fatigue was significantly correlated with poor sleep quality (MFIS: F = 15.60, P < 0.01; FSS: F = 12.09, P < 0.01). FSS scores were also significantly correlated with the PSQI subscore for daytime dysfunction and MFIS scores were significantly correlated with disability, age, and the PSQI subscores for sleep quality, sleep duration, and daytime dysfunction. Conclusions. This study demonstrates a relationship between fatigue and sleep quality in individuals with MS and cognitive impairment.
背景。疲劳是多发性硬化症（MS）患者最常见的症状。该人群中也存在睡眠不佳的情况。目的。本研究的目的是确定MS合并认知障碍患者的疲劳与睡眠质量之间的关系。方法。这项横断面研究评估了121名MS合并认知障碍患者的疲劳（采用改良疲劳影响量表（MFIS）和疲劳严重程度量表（FSS）进行评估）、睡眠质量（采用匹兹堡睡眠质量指数（PSQI）进行评估）以及人口统计学特征之间的关系。结果。疲劳与睡眠质量差显著相关（MFIS：F = 15.60，P < 0.01；FSS：F = 12.09，P < 0.01）。FSS评分也与PSQI中的日间功能障碍子评分显著相关，MFIS评分与残疾、年龄以及PSQI中的睡眠质量、睡眠时间和日间功能障碍子评分显著相关。结论。本研究证明了MS合并认知障碍个体的疲劳与睡眠质量之间的关系。
