Radiobiol Radiother (Berl). 1989;30(2):163-6.
Radiation induced changes in the testicular RNA content of whole body irradiated Swiss albino mouse and their modification by a thiophosphate, WR-2721 were studied. Three different doses of gamma radiation were given for the purpose. The RNA content of the testis was found to be affected adversely after irradiation. It was observed that the drug inhibited the alterations in the RNA content to a significant extent. Degree of protection and possible mechanisms of action have been discussed.
研究了全身照射的瑞士白化小鼠睾丸RNA含量的辐射诱导变化以及硫代磷酸盐WR-2721对其的修饰作用。为此给予了三种不同剂量的γ辐射。发现照射后睾丸的RNA含量受到不利影响。观察到该药物在很大程度上抑制了RNA含量的变化。讨论了保护程度和可能的作用机制。
