Shen Zhi-Gang, Wang Han-Ping
Aquaculture Genetics and Breeding Laboratory, The Ohio State University South Centers, Piketon, Ohio 45661, USA.
Genet Sel Evol. 2014 Apr 15;46(1):26. doi: 10.1186/1297-9686-46-26.
The molecular mechanisms that underlie sex determination and differentiation are conserved and diversified. In fish species, temperature-dependent sex determination and differentiation seem to be ubiquitous and molecular players involved in these mechanisms may be conserved. Although how the ambient temperature transduces signals to the undifferentiated gonads remains to be elucidated, the genes downstream in the sex differentiation pathway are shared between sex-determining mechanisms. In this paper, we review recent advances on the molecular players that participate in the sex determination and differentiation in fish species, by putting emphasis on temperature-dependent sex determination and differentiation, which include temperature-dependent sex determination and genetic sex determination plus temperature effects. Application of temperature-dependent sex differentiation in farmed fish and the consequences of temperature-induced sex reversal are discussed.
性别决定和分化背后的分子机制既有保守性又有多样性。在鱼类物种中，温度依赖性性别决定和分化似乎普遍存在，参与这些机制的分子成分可能是保守的。尽管环境温度如何将信号传导至未分化的性腺仍有待阐明，但性别分化途径下游的基因在性别决定机制之间是共享的。在本文中，我们回顾了参与鱼类性别决定和分化的分子成分的最新进展，重点关注温度依赖性性别决定和分化，其中包括温度依赖性性别决定以及遗传性别决定加上温度效应。讨论了温度依赖性性别分化在养殖鱼类中的应用以及温度诱导性逆转的后果。
