Core Facility Molecular Biology, Center for Medical Research, Medical University of Graz, Graz, Austria.
Department of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
PLoS Med. 2014 Apr 15;11(4):e1001627. doi: 10.1371/journal.pmed.1001627. eCollection 2014 Apr.
Christoph Steininger and colleagues explore how multiple infectious, autoimmune, metabolic, and neoplastic diseases have been associated with changes in the intestinal microbiome, although a cause-effect relationship is often difficult to establish. Integration of metagenomics into clinical medicine is a challenge, and the authors highlight clinical approaches that are of high priority for the useful medical application of metagenomics. Please see later in the article for the Editors' Summary.
克里斯托夫·施泰宁格及其同事探讨了多种感染性、自身免疫性、代谢性和肿瘤性疾病如何与肠道微生物组的变化相关联，尽管通常很难确定因果关系。将宏基因组学整合到临床医学中是一个挑战，作者强调了对于宏基因组学的有用医学应用具有高优先级的临床方法。请在文章后面查看编辑摘要。
