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神经递质的化学传感。

Chemical sensing of neurotransmitters.

机构信息

Department of Chemistry, Korea University, Seoul 130-701, Korea.

出版信息

Chem Soc Rev. 2014 Jul 7;43(13):4684-713. doi: 10.1039/c3cs60477b. Epub 2014 Apr 16.

DOI:10.1039/c3cs60477b
PMID:24736802
Abstract

In the past few decades, the development of chemosensors for neurotransmitters has emerged as a research area of significant importance, which attracted a tremendous amount of attention due to its high sensitivity and rapid response. This current review focuses on various neurotransmitter detection based on fluorescent or colorimetric spectrophotometry published for the last 12 years, covering biogenic amines (dopamine, epinephrine, norepinephrine, serotonin, histamine and acetylcholine), amino acids (glutamate, aspartate, GABA, glycine and tyrosine), and adenosine.

摘要

在过去几十年中,神经递质化学传感器的发展已经成为一个非常重要的研究领域,由于其高灵敏度和快速响应,引起了极大的关注。本综述重点介绍了过去 12 年来基于荧光或比色分光光度法的各种神经递质检测,涵盖了生物胺(多巴胺、肾上腺素、去甲肾上腺素、血清素、组胺和乙酰胆碱)、氨基酸(谷氨酸、天冬氨酸、GABA、甘氨酸和酪氨酸)和腺苷。

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