Design and Fabrication of α-MnO-Nanorods-Modified Glassy-Carbon-Electrode-Based Serotonin Sensor.

Serotonin is a very important monoamine neurotransmitter, which takes part in biological and psychological processes. In the present scenario, design and fabrication of a serotonin electrochemical sensor is of great significance. In this study, we have synthesized α-MnO via a hydrothermal synthesis method using potassium permanganate as a precursor. The physiochemical properties, such as structural and phase-purity of the prepared α-MnO, were investigated by various characterization techniques and methods (powder X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy). Furthermore, the serotonin sensor was fabricated using α-MnO as an electrode modifier or electro-catalyst. The bare glassy carbon electrode (GCE) was adopted as a working substrate, and its active carbon surface was modified with the synthesized α-MnO. This modified GCE () was explored as a serotonin sensor. The electrochemical investigations showed that the has excellent electro-catalytic properties towards determination of serotonin. The exhibits an excellent detection limit (DL) of 0.14 µM, along with good sensitivity of 2.41 µAµM cm. The also demonstrated excellent selectivity for determination of serotonin in the presence of various electro-active/interfering molecules. The also exhibits good cyclic repeatability, stability, and storage stability.