推测由棕色隐遁蛛咬伤引起的继发性噬血细胞性淋巴组织细胞增生症（HLH）。
Secondary hemophagocytic lymphohistiocytosis (HLH) from a presumed brown recluse spider bite.
作者信息
Dandoy Christopher, Grimley Michael
机构信息
Department of Pediatrics, Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7015, 45229, Cincinnati, OH, USA,
出版信息
J Clin Immunol. 2014 Jul;34(5):544-7. doi: 10.1007/s10875-014-0036-1. Epub 2014 Apr 16.
Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We present a case of a 10-year-old male that developed presumed systemic loxoscelism, secondary hemophagocytic lymphohistiocytosis with hepatic dysfunction and renal failure. He was treated with dexamethasone and made a full recovery.
全身性褐蛛中毒是褐蛛（棕色遁蛛）咬伤后罕见的并发症。褐蛛毒液含有促炎蛋白，在噬血细胞性淋巴组织细胞增生症患者中这些蛋白水平已被证实会升高。我们报告一例10岁男性病例，该患者出现疑似全身性褐蛛中毒，继发噬血细胞性淋巴组织细胞增生症并伴有肝功能障碍和肾衰竭。他接受了地塞米松治疗并完全康复。
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