Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.
Asian J Androl. 2018 Jul-Aug;20(4):379-384. doi: 10.4103/aja.aja_80_17.
The present study aims to analyze sperm concentration trends among young and healthy Chinese adults in Wuhan, Central China, from 2010 to 2015. Semen analysis data from 9357 participants were collected and analyzed using a general linear model and the Cochran-Armitage trend test. A significant decline was observed in sperm concentration (β [standard deviation]: -1.53 [0.16]; P < 0.001). In addition, a decline in sperm density was observed by stratifying student versus nonstudent sperm donors and by analyzing the year of birth or birth year cohort of the participants. Furthermore, the percentage of participants with sperm densities of over 40 × 10 ml significantly decreased with year. Notably, a dramatic decline in sperm density was recorded over the first 5 years of study. This research reported a decline in sperm concentration among young adults in Wuhan, Central China, in 2010-2015.
本研究旨在分析 2010 至 2015 年间中国中部武汉市年轻健康成年人的精子浓度趋势。收集了 9357 名参与者的精液分析数据，并使用一般线性模型和 Cochran-Armitage 趋势检验进行了分析。结果显示，精子浓度呈显著下降趋势（β[标准差]：-1.53[0.16]；P<0.001）。此外，通过对学生与非学生精子供体进行分层分析，以及对参与者的出生年份或出生年份队列进行分析，也观察到精子密度的下降。此外，精子密度超过 40×10/ml 的参与者比例也随年份显著下降。值得注意的是，在研究的前 5 年中，精子密度急剧下降。本研究报告了 2010-2015 年间中国中部武汉市年轻成年人精子浓度的下降。
