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波兰波兹南临床醋酸钙不动杆菌-鲍曼不动杆菌复合体的1类整合子与抗生素耐药性

Class 1 integrons and antibiotic resistance of clinical Acinetobacter calcoaceticus-baumannii complex in Poznań, Poland.

作者信息

Koczura Ryszard, Przyszlakowska Beata, Mokracka Joanna, Kaznowski Adam

机构信息

Department of Microbiology, Faculty of Biology, Adam Mickiewicz University in Poznań, ul Umultowska 89, 61-614, Poznan, Poland,

出版信息

Curr Microbiol. 2014 Sep;69(3):258-62. doi: 10.1007/s00284-014-0581-0. Epub 2014 Apr 17.

DOI:10.1007/s00284-014-0581-0
PMID:24740302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4113676/
Abstract

Sixty-three clinical isolates of Acinetobacter calcoaceticus-baumannii complex were analyzed for the presence of integrons and antimicrobial resistance. Class 1 integrons were detected in 40 (63.5 %) isolates. None of them had class 2 or class 3 integrons. The majority of the integrons contained aacC1-orfA-orfB-aadA1 gene cassette array. The presence of integrons was associated with the increased frequency of resistance to 12 of 15 antimicrobials tested, multi-drug resistance phenotype, and the overall resistance ranges of the strains.

摘要

对63株醋酸钙不动杆菌-鲍曼不动杆菌复合体临床分离株进行整合子检测及耐药性分析。40株（63.5%）分离株检测到1类整合子。未检测到2类或3类整合子。大多数整合子含有aacC1-orfA-orfB-aadA1基因盒阵列。整合子的存在与受试15种抗菌药物中12种的耐药频率增加、多重耐药表型以及菌株的总体耐药范围有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e0a/4113676/924054ec0e60/284_2014_581_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e0a/4113676/924054ec0e60/284_2014_581_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e0a/4113676/924054ec0e60/284_2014_581_Fig1_HTML.jpg

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