Koczura Ryszard, Przyszlakowska Beata, Mokracka Joanna, Kaznowski Adam
Department of Microbiology, Faculty of Biology, Adam Mickiewicz University in Poznań, ul Umultowska 89, 61-614, Poznan, Poland,
Curr Microbiol. 2014 Sep;69(3):258-62. doi: 10.1007/s00284-014-0581-0. Epub 2014 Apr 17.
Sixty-three clinical isolates of Acinetobacter calcoaceticus-baumannii complex were analyzed for the presence of integrons and antimicrobial resistance. Class 1 integrons were detected in 40 (63.5 %) isolates. None of them had class 2 or class 3 integrons. The majority of the integrons contained aacC1-orfA-orfB-aadA1 gene cassette array. The presence of integrons was associated with the increased frequency of resistance to 12 of 15 antimicrobials tested, multi-drug resistance phenotype, and the overall resistance ranges of the strains.
对63株醋酸钙不动杆菌-鲍曼不动杆菌复合体临床分离株进行整合子检测及耐药性分析。40株(63.5%)分离株检测到1类整合子。未检测到2类或3类整合子。大多数整合子含有aacC1-orfA-orfB-aadA1基因盒阵列。整合子的存在与受试15种抗菌药物中12种的耐药频率增加、多重耐药表型以及菌株的总体耐药范围有关。