Greco Filippo, Cocuzza Maria Donatella, Smilari Pierluigi, Sorge Giovanni, Pavone Lorenzo
Unit of Clinical Pediatrics, Department of Medical and Pediatric Sciences, University of Catania, Via Santa Sofia, 95123 Catania, Italy.
Unit of Child Neuropsychiatry, Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy.
Case Rep Pediatr. 2014;2014:547396. doi: 10.1155/2014/547396. Epub 2014 Mar 12.
Children with acute encephalopathy show prolonged electrographic seizure activity consistent with nonconvulsive status epilepticus (NCSE). Pediatric NCSE is a heterogeneous clinical entity with poor outcome and different etiologies, including central nervous system infection, stroke, toxic-metabolic syndrome, and epileptic syndrome. We report a 4-year-old girl with seizure and behavioral changes in whom the analysis of cerebrospinal fluid by polymerase chain reaction was positive for Epstein-Barr virus. We emphasize the importance of electroencephalography (EEG), and particularly, of continuous EEG monitoring for early recognition and appropriate treatment of this condition.
患有急性脑病的儿童表现出与非惊厥性癫痫持续状态（NCSE）一致的长时间脑电图癫痫活动。小儿NCSE是一种临床异质性疾病，预后较差，病因各异，包括中枢神经系统感染、中风、中毒代谢综合征和癫痫综合征。我们报告了一名4岁女童，有癫痫发作和行为改变，其脑脊液经聚合酶链反应分析显示爱泼斯坦-巴尔病毒呈阳性。我们强调脑电图（EEG）的重要性，尤其是持续脑电图监测对于早期识别和适当治疗这种疾病的重要性。
