Verhoeven Frank, Prati Clément, Wendling Daniel
Rhumatologie, CHU Jean Minjoz, 2 Boulevard Fleming, 25030 Besançon, France.
Case Rep Rheumatol. 2014;2014:424056. doi: 10.1155/2014/424056. Epub 2014 Mar 16.
We report a case of a spontaneous hip fracture in a context of dysglobulinemia. The bone histologic examination found amyloidoma. Amyloidoma is an overload pathology and an unusual cause of fracture. In most of the cases, it is associated with myeloma and the difference between bone invasion of myeloma and amyloidoma in an osteolytic radiographic picture is not easy but is of importance because prognosis and treatment may be totally different. Thus, in the context of dysglobulinemia, one must keep in mind that spontaneous bone fracture may be due to amyloidoma with another prognosis.
我们报告了一例在球蛋白异常血症背景下发生的自发性髋部骨折病例。骨组织学检查发现了淀粉样瘤。淀粉样瘤是一种负荷过重的病理状态，也是一种不常见的骨折原因。在大多数情况下，它与骨髓瘤相关，在溶骨性影像学表现中，骨髓瘤和淀粉样瘤的骨侵犯鉴别并不容易，但却很重要，因为预后和治疗可能完全不同。因此，在球蛋白异常血症的背景下，必须牢记自发性骨折可能是由淀粉样瘤引起的，且预后不同。
