Lai K N, Chan K W, Siu D L, Wong C C, Yeung D
Am J Med. 1984 Nov;77(5):937-43. doi: 10.1016/0002-9343(84)90546-1.
Amyloidoma primarily involving bone and lymph node is described in a 60-year-old male patient. The patient had pathologic fractures of both hips through a deposit of amyloid in the neck of the femur. The prolonged insidious course of the disease was uncomplicated by hypercalcemia, hematologic abnormalities, or renal failure so characteristic of untreated myeloma. The bone marrow contained less than 10 percent plasma cells in different stages of maturity. Radionuclide bone scanning demonstrated other osseous amyloid lesions that were not detected by routine radiologic examination. This is the first reported case of pathologic fractures of both hips secondary to amyloidoma.
一名60岁男性患者被诊断为主要累及骨骼和淋巴结的淀粉样瘤。患者双侧髋部因股骨颈淀粉样物质沉积而发生病理性骨折。该疾病病程隐匿且漫长，未出现高钙血症、血液学异常或肾衰竭等未经治疗的骨髓瘤所特有的并发症。骨髓中不同成熟阶段的浆细胞少于10%。放射性核素骨扫描显示出其他常规放射学检查未发现的骨淀粉样病变。这是首例因淀粉样瘤继发双侧髋部病理性骨折的报道病例。
