类风湿关节炎患者在使用依那西普治疗期间发生的急性眼肌炎。
Acute ocular myositis occurring under etanercept for rheumatoid arthritis.
作者信息
Couderc Marion, Mathieu Sylvain, Tournadre Anne, Dubost Jean-Jacques, Soubrier Martin
机构信息
Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
Rheumatology Department, Clermont-Ferrand Teaching Hospital, place Henri-Dunant, 63000 Clermont-Ferrand, France.
出版信息
Joint Bone Spine. 2014 Oct;81(5):445-6. doi: 10.1016/j.jbspin.2014.03.003. Epub 2014 Apr 18.
Ocular myositis is a rare disorder characterized by inflammation of single or multiple extra-ocular eye muscles presenting with painful diplopia and/or ophthalmoplegia. The etiology remains obscure and it is rarely associated with rheumatoid arthritis. We here reported the case of a 61-year-old woman treated by TNF-α blockade, namely etanercept, for rheumatoid arthritis for ten years who developed an acute ocular myositis. The patient improved after etanercept was stopped and initiation of high doses of corticosteroids. To our knowledge, this is the second report of ocular myositis occurring under TNF-α blockade treatment for rheumatoid arthritis.
眼肌炎是一种罕见的疾病，其特征为单条或多条眼外肌发生炎症，伴有疼痛性复视和/或眼肌麻痹。病因尚不明确，且很少与类风湿性关节炎相关。我们在此报告一例61岁女性患者，她因类风湿性关节炎接受肿瘤坏死因子-α（TNF-α）拮抗剂依那西普治疗10年后，发生了急性眼肌炎。停用依那西普并开始使用大剂量皮质类固醇后，患者病情好转。据我们所知，这是第二例在TNF-α拮抗剂治疗类风湿性关节炎过程中发生眼肌炎的报告。
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