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离家外出的男性更有可能将疟疾传入埃塞俄比亚西北部的高海拔村庄。

Men traveling away from home are more likely to bring malaria into high altitude villages, northwest Ethiopia.

作者信息

Alemu Kassahun, Worku Alemayehu, Berhane Yemane, Kumie Abera

机构信息

Department of Environmental and Occupational Health and Safety, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

PLoS One. 2014 Apr 18;9(4):e95341. doi: 10.1371/journal.pone.0095341. eCollection 2014.

Abstract

BACKGROUND

Information about malaria risk factors at high altitudes is scanty. Understanding the risk factors that determine the risk of malaria transmission at high altitude villages is important to facilitate implementing sustainable malaria control and prevention programs.

METHODS

An unmatched case control study was conducted among patients seeking treatment at health centers in high altitude areas. Either microscopy or rapid diagnostic tests were used to confirm the presence of plasmodium species. A generalized linear model was used to identify the predictors of malaria transmission in high altitude villages.

RESULTS

Males (AOR = 3.11, 95%CI: 2.28, 4.23), and those who traveled away from the home in the previous month (AOR = 2.01, 95% CI: 1.56, 2.58) were strongly associated with presence of malaria in high altitude villages. Other significant factors, including agriculture in occupation (AOR = 1.41, 95% CI: 1.05, 1.93), plants used for fencing (AOR = 1.70, 95% CI: 1.18, 2.52) and forests near the house (AOR = 1.60, 95% CI: 1.15, 2.47), were found predictors for malaria in high altitude villages.

CONCLUSION

Travel outside of their home was an important risk of malaria infections acquisition. Targeting males who frequently travel to malarious areas can reduce malaria transmission risks in high altitude areas.

摘要

背景

关于高海拔地区疟疾风险因素的信息匮乏。了解决定高海拔村庄疟疾传播风险的因素对于推动实施可持续的疟疾控制和预防计划至关重要。

方法

在高海拔地区的医疗中心对寻求治疗的患者进行了一项非匹配病例对照研究。使用显微镜检查或快速诊断测试来确认疟原虫种类的存在。采用广义线性模型来确定高海拔村庄疟疾传播的预测因素。

结果

男性(调整后比值比[AOR] = 3.11,95%置信区间[CI]:2.28,4.23)以及前一个月离家出行的人(AOR = 2.01,95% CI:1.56,2.58)与高海拔村庄疟疾的存在密切相关。其他显著因素,包括从事农业(AOR = 1.41,95% CI:1.05,1.93)、用于围栏的植物(AOR = 1.70,95% CI:1.18,2.52)和房屋附近的森林(AOR = 1.60,95% CI:1.15,2.47),被发现是高海拔村庄疟疾的预测因素。

结论

离家外出是感染疟疾的一个重要风险。针对经常前往疟疾流行地区的男性可以降低高海拔地区的疟疾传播风险。

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