Patel Ruchir, Ede Jessica, Collins Joshua, Willens David
Department of Internal Medicine, Henry Ford Hospital, Detroit, Mich., USA.
Case Rep Oncol. 2014 Mar 13;7(1):171-4. doi: 10.1159/000360812. eCollection 2014 Jan.
Pancreatic adenocarcinoma has an incidence rate nearly equal to the mortality rate and is the fourth leading cause of cancer-related death in the USA. This is largely due to late symptom onset and diagnosis. Evidence has emerged that new-onset diabetes may be a symptom caused by occult pancreatic cancer. We report the case of a middle-aged African American female who presented with hyperglycemia and persistent scapular tenderness. She was subsequently diagnosed with new-onset diabetes and metastatic pancreatic cancer confirmed by liver biopsy. She did not have diabetes or pre-diabetes in the 6 months prior to presentation. The following report will serve to emphasize the role of new-onset diabetes in certain patients as a warning sign necessitating further investigation for pancreatic cancer. New-onset diabetes associated with specific risk factors may prompt for early testing, detection and treatment of pancreatic cancer.
胰腺腺癌的发病率几乎与死亡率相当，是美国癌症相关死亡的第四大主要原因。这主要是由于症状出现较晚以及诊断较迟。有证据表明，新发糖尿病可能是隐匿性胰腺癌引起的一种症状。我们报告了一例中年非裔美国女性病例，该患者表现为高血糖和持续的肩胛部压痛。随后她被诊断为新发糖尿病，经肝活检确诊为转移性胰腺癌。在就诊前6个月，她没有糖尿病或糖尿病前期。以下报告将强调新发糖尿病在某些患者中作为胰腺癌警示信号的作用，需要进一步检查。与特定风险因素相关的新发糖尿病可能促使对胰腺癌进行早期检测、诊断和治疗。
