Department of Organic Psychiatric Disorders and Emergency Ward, Aarhus University Hospital, Risskov, Denmark.
Acta Psychiatr Scand. 2014 Aug;130(2):87-98. doi: 10.1111/acps.12281. Epub 2014 Apr 21.
This article illustrates the development of psychiatric register research and discusses the strengths, limitations, and possible directions for future activities.
Examples illustrating the development from the post-World War II introduction of psychiatric register research until today are selected.
The strengths of register research are seen especially within health service. Until recently, when starting linking registers to biobanks, register research had limited value in cause-seeking. Register research benefits from the possibilities for following identifiable persons over long time (lifelong) and the possibilities for linking to other registers and databases. Important limitations of register research are the heterogeneity and questionable validity of the clinical data collected.
Future register research can go in the direction of big is beautiful collecting data from all possible sources creating giga-registers. In that case, low data quality will still be an unsolved problem. Or it can take the direction of smaller local clinical databases which has many advantages, for example, integrating clinical knowledge and experience into register research. However, in that case, registers will not be able to deal with rare conditions and diseases.
本文阐述了精神科登记研究的发展，并讨论了其优势、局限性以及未来活动的可能方向。
选择了一些例子来说明从二战后引入精神科登记研究到今天的发展过程。
登记研究的优势尤其体现在卫生服务领域。直到最近，当开始将登记与生物库联系起来时，病因研究的登记研究价值有限。登记研究受益于对可识别人员进行长期（终身）随访的可能性，以及与其他登记和数据库联系的可能性。登记研究的重要局限性是所收集的临床数据的异质性和可疑的有效性。
未来的登记研究可以朝着“大即是美”的方向发展，从所有可能的来源收集数据，创建大型登记库。在这种情况下，数据质量低仍然是一个未解决的问题。或者它可以朝着更小的本地临床数据库的方向发展，这有很多优势，例如，将临床知识和经验融入登记研究。然而，在这种情况下，登记处将无法处理罕见的病症。
