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Big data for bipolar disorder.双相障碍的大数据。
Int J Bipolar Disord. 2016 Dec;4(1):10. doi: 10.1186/s40345-016-0051-7. Epub 2016 Apr 11.
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Big data are coming to psychiatry: a general introduction.大数据正在进入精神病学领域:概论。
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Advancing biomarker research: utilizing 'Big Data' approaches for the characterization and prevention of bipolar disorder.推进生物标志物研究:利用“大数据”方法对双相情感障碍进行特征描述与预防。
Bipolar Disord. 2014 Aug;16(5):531-47. doi: 10.1111/bdi.12162. Epub 2013 Dec 16.
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Int J Risk Saf Med. 2015;27 Suppl 1:S108-9. doi: 10.3233/JRS-150711.

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Natural Language Processing Methods and Bipolar Disorder: Scoping Review.自然语言处理方法与双相情感障碍:范围综述
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Digital health developments and drawbacks: a review and analysis of top-returned apps for bipolar disorder.数字健康的发展与弊端:双相情感障碍顶级热门应用的综述与分析
Int J Bipolar Disord. 2020 Dec 1;8(1):39. doi: 10.1186/s40345-020-00202-4.
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Survey of psychiatrist use of digital technology in clinical practice.精神科医生在临床实践中使用数字技术的调查。
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Initial and relapse prodromes in adult patients with episodes of bipolar disorder: A systematic review.成人双相情感障碍发作患者的首发和复发前驱症状:系统综述。
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Vibration of effects in epidemiologic studies of alcohol consumption and breast cancer risk.饮酒与乳腺癌风险的流行病学研究中效应的振动。
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Smartphones in mental health: a critical review of background issues, current status and future concerns.智能手机在心理健康领域的应用:对背景问题、现状及未来关注点的批判性综述
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J Med Internet Res. 2018 Jul 30;20(7):e10131. doi: 10.2196/10131.

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Childhood IQ and risk of bipolar disorder in adulthood: prospective birth cohort study.儿童期智商与成年后患双相情感障碍的风险:前瞻性出生队列研究
BJPsych Open. 2015 Aug 20;1(1):74-80. doi: 10.1192/bjpo.bp.115.000455. eCollection 2015 Jun.
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ECOLOGICALLY VALID LONG-TERM MOOD MONITORING OF INDIVIDUALS WITH BIPOLAR DISORDER USING SPEECH.使用语音对双相情感障碍个体进行生态有效长期情绪监测。
Proc IEEE Int Conf Acoust Speech Signal Process. 2014 May;2014:4858-4862. doi: 10.1109/ICASSP.2014.6854525. Epub 2014 Jul 14.
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Methodological challenges and analytic opportunities for modeling and interpreting Big Healthcare Data.用于建模和解读大型医疗保健数据的方法挑战与分析机遇
Gigascience. 2016 Feb 25;5:12. doi: 10.1186/s13742-016-0117-6. eCollection 2016.
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Big Data, Small Effects.大数据,小效应。
J Clin Oncol. 2016 Apr 10;34(11):1170-1. doi: 10.1200/JCO.2015.65.8161. Epub 2016 Feb 16.
5
Subcortical volumetric abnormalities in bipolar disorder.双相情感障碍中的皮质下体积异常。
Mol Psychiatry. 2016 Dec;21(12):1710-1716. doi: 10.1038/mp.2015.227. Epub 2016 Feb 9.
6
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.双相情感障碍中与锂盐治疗反应相关的基因变异:一项全基因组关联研究。
Lancet. 2016 Mar 12;387(10023):1085-1093. doi: 10.1016/S0140-6736(16)00143-4. Epub 2016 Jan 22.
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Diabetes Screening Among Underserved Adults With Severe Mental Illness Who Take Antipsychotic Medications.服用抗精神病药物的未得到充分服务的重度精神疾病成年人的糖尿病筛查
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Use of Lithium and Anticonvulsants and the Rate of Chronic Kidney Disease: A Nationwide Population-Based Study.锂和抗惊厥药物的使用与慢性肾脏病的发生率:一项全国范围内基于人群的研究。
JAMA Psychiatry. 2015 Dec;72(12):1182-91. doi: 10.1001/jamapsychiatry.2015.1834.
9
Lithium and renal and upper urinary tract tumors - results from a nationwide population-based study.锂与肾脏及上尿路肿瘤——一项基于全国人口的研究结果
Bipolar Disord. 2015 Dec;17(8):805-13. doi: 10.1111/bdi.12344. Epub 2015 Nov 3.
10
Long-term effect of lithium maintenance therapy on estimated glomerular filtration rate in patients with affective disorders: a population-based cohort study.锂盐维持治疗对情感障碍患者估计肾小球滤过率的长期影响:一项基于人群的队列研究。
Lancet Psychiatry. 2015 Dec;2(12):1075-83. doi: 10.1016/S2215-0366(15)00316-8. Epub 2015 Oct 6.

双相障碍的大数据。

Big data for bipolar disorder.

机构信息

Michigan State University College of Human Medicine, Traverse City Campus, 1400 Medical Campus Drive, Traverse City, MI, 49684, USA.

ChronoRecord Association, Inc, Fullerton, CA, 92834, USA.

出版信息

Int J Bipolar Disord. 2016 Dec;4(1):10. doi: 10.1186/s40345-016-0051-7. Epub 2016 Apr 11.

DOI:10.1186/s40345-016-0051-7
PMID:27068058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4828347/
Abstract

The delivery of psychiatric care is changing with a new emphasis on integrated care, preventative measures, population health, and the biological basis of disease. Fundamental to this transformation are big data and advances in the ability to analyze these data. The impact of big data on the routine treatment of bipolar disorder today and in the near future is discussed, with examples that relate to health policy, the discovery of new associations, and the study of rare events. The primary sources of big data today are electronic medical records (EMR), claims, and registry data from providers and payers. In the near future, data created by patients from active monitoring, passive monitoring of Internet and smartphone activities, and from sensors may be integrated with the EMR. Diverse data sources from outside of medicine, such as government financial data, will be linked for research. Over the long term, genetic and imaging data will be integrated with the EMR, and there will be more emphasis on predictive models. Many technical challenges remain when analyzing big data that relates to size, heterogeneity, complexity, and unstructured text data in the EMR. Human judgement and subject matter expertise are critical parts of big data analysis, and the active participation of psychiatrists is needed throughout the analytical process.

摘要

精神科护理的提供正在发生变化,新的重点是综合护理、预防措施、人群健康和疾病的生物学基础。这一转变的基础是大数据和分析这些数据的能力的进步。本文讨论了大数据对目前和不久的将来双相情感障碍常规治疗的影响,其中包括与卫生政策、新关联的发现以及罕见事件研究相关的例子。目前大数据的主要来源是电子病历 (EMR)、提供者和支付者的索赔和登记数据。在不久的将来,患者通过主动监测、互联网和智能手机活动的被动监测以及传感器创建的数据可能会与 EMR 集成。来自医学以外的各种数据源,如政府财务数据,将被用于研究。从长远来看,遗传和成像数据将与 EMR 集成,预测模型将更加重视。在分析与 EMR 中的大小、异质性、复杂性和非结构化文本数据相关的大数据时,仍然存在许多技术挑战。人类判断和主题专业知识是大数据分析的关键部分,精神病学家需要在整个分析过程中积极参与。