Lee Kangho, Nair Pradeep R, Scott Adina, Alam Muhammad A, Janes David B
J Appl Phys. 2009 May 15;105(10):102046. doi: 10.1063/1.3116630. Epub 2009 May 19.
Design and fabrication of electronic biosensors based on field-effect-transistor (FET) devices require understanding of interactions between semiconductor surfaces and organic biomolecules. From this perspective, we review practical considerations for electronic biosensors with emphasis on molecular passivation effects on FET device characteristics upon immobilization of organic molecules and an electrostatic model for FET-based biosensors.
基于场效应晶体管(FET)器件的电子生物传感器的设计与制造需要了解半导体表面与有机生物分子之间的相互作用。从这个角度出发,我们回顾了电子生物传感器的实际考量因素,重点关注有机分子固定后对FET器件特性的分子钝化效应以及基于FET的生物传感器的静电模型。