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先天性铅中毒:一种不寻常的表现。

Congenital lead poisoning: an unusual presentation.

作者信息

Mazumdar Ipsita, Goswami K

机构信息

Department of Biochemistry, KPC Medical College & Hospital, Jadavpur, West Bengal India.

Department of Pathology, ESIC Hospital & ODC (EZ), Joka, Kolkata, India.

出版信息

Indian J Clin Biochem. 2014 Apr;29(2):257-9. doi: 10.1007/s12291-013-0374-4. Epub 2013 Aug 29.

Abstract

Lead poisoning presents a common acquired as well as congenital environmental threat to children's health today. An unusual case of severe lead poisoning in breast fed male infant is presented here. The objective of the study is to describe a patient who developed clinical lead intoxication with an uncommon source of poisoning. A 6 months old male baby presented with gradual loss of weight, not feeding well and persistent vomiting. Laboratory investigation revealed that he was having anemia (Hb level 5.4 gm/dl), abnormal liver enzymes (including elevated transaminase activity) and high blood lead value (83 μg/dl). RBC morphology showed basophilic stippling with cabot ring, suggestive of a case of lead poisoning. A course of chelation treatment using calcium versenate (EDTACaNa2) was prescribed following which a radical solution for mobilization of lead from his systems was observed.

摘要

铅中毒如今是对儿童健康常见的后天性以及先天性环境威胁。本文呈现了一例母乳喂养男婴严重铅中毒的罕见病例。该研究的目的是描述一名因不寻常中毒源而发生临床铅中毒的患者。一名6个月大的男婴出现体重逐渐减轻、喂养不佳和持续呕吐。实验室检查显示他患有贫血(血红蛋白水平5.4克/分升)、肝酶异常(包括转氨酶活性升高)以及高血铅值(83微克/分升)。红细胞形态显示有嗜碱性点彩和卡波环,提示为铅中毒病例。随后开了使用依地酸钙钠(EDTACaNa2)的螯合治疗疗程,之后观察到从他体内排出铅的根本解决办法。

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本文引用的文献

1
Eye cosmetic 'surma': hidden threats of lead poisoning.
Indian J Clin Biochem. 2013 Jan;28(1):71-3. doi: 10.1007/s12291-012-0235-6. Epub 2012 Aug 2.
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Lead toxicity as a result of herbal medication.
Indian J Clin Biochem. 2008 Apr;23(2):200-3. doi: 10.1007/s12291-008-0045-z. Epub 2008 Jun 11.
3
Hepatorenal dysfunctions in lead pollution.
J Environ Sci Eng. 2005 Jan;47(1):75-80.

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