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印度尼西亚雅加达产妇中乙肝感染的当前流行情况。

Current prevalence of hepatitis B infection among parturient women in Jakarta, Indonesia.

作者信息

Gunardi Hartono, Zaimi Liza F, Harahap Alida R, Muljono David H

机构信息

Department of Child Health, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

出版信息

Acta Med Indones. 2014 Jan;46(1):3-9.

Abstract

AIM

to determine the current prevalence of hepatitis B infection among parturient women in Jakarta, Indonesia.

METHODS

a cross-sectional study was conducted in women giving birth between May and July 2009, recruited by consecutive sampling technique in 2 hospitals and 13 public health centers in Jakarta. Mothers with history of chronic liver disease were excluded. Data were collected by questionnaires including obstetric history, hepatitis B immunization history, and the presence of jaundice; maternal venous blood samples were taken before parturition for HBsAg determination that was performed by ELISA.

RESULTS

of 1,009 parturient women screened for hepatitis B infection, 22 were found positive, giving an overall hepatitis B prevalence of 2.2%, previous 5.2% in 1985. None of the subjects had any symptoms of HBV infection. The highest HBsAg prevalence was found in the East Jakarta study site, with predominance in mothers aged <20 years and those with multi-parities.

CONCLUSION

present prevalence of HBsAg among Indonesian parturient women in Jakarta was 2.2% and markedly reduced compared with prevalence in 1985.

摘要

目的

确定印度尼西亚雅加达产妇中乙型肝炎感染的当前流行率。

方法

于2009年5月至7月对分娩女性进行了一项横断面研究,通过连续抽样技术在雅加达的2家医院和13个公共卫生中心招募研究对象。排除有慢性肝病病史的母亲。通过问卷调查收集数据,包括产科病史、乙型肝炎免疫史和黄疸情况;在分娩前采集母亲静脉血样本,采用酶联免疫吸附测定法(ELISA)检测HBsAg。

结果

在1009名接受乙型肝炎感染筛查的产妇中,22人检测呈阳性,乙型肝炎总体流行率为2.2%,1985年为5.2%。所有研究对象均无任何HBV感染症状。在雅加达东部研究地点发现HBsAg流行率最高,以年龄小于20岁的母亲和多产妇为主。

结论

雅加达印度尼西亚产妇中HBsAg的当前流行率为2.2%,与1985年的流行率相比显著降低。

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