Ma W X, Li W
Zhonghua Bing Li Xue Za Zhi. 1989 Mar;18(1):37-9.
Both prostate specific acid phosphatase (PAP) and prostate specific anti-body (PSA) were used as the specific markers for detecting prostate cancer and its metastasis, and this was considered as the most efficient technique for detecting metastatic lesions associated with an occult carcinoma in the prostate. Altogether 44 cases were studied, including 23 cases of prostatic carcinoma, 3 cases of metastatic tumors and 18 cases of benign hypertrophy of prostate (including 4 cases with local carcinoma). Analysis of 27 cases revealed that PSA seemed more sensitive than PAP, as 17 cases of prostatic carcinoma showed positive reaction with PSA, while among them, only 3 showed negative reaction with PAP. Most of the well differentiated glandular type prostatic carcinoma showed strong positive reaction. However, the poorly differentiated solid carcinoma only showed mild positive reaction. All of the controls as well as bladder and kidney cancers showed negative reaction with either PAP or PSA.
前列腺特异性酸性磷酸酶（PAP）和前列腺特异性抗体（PSA）均被用作检测前列腺癌及其转移的特异性标志物，并且这被认为是检测与前列腺隐匿癌相关的转移病变的最有效技术。共研究了44例病例，包括23例前列腺癌、3例转移瘤和18例前列腺良性增生（包括4例局部癌）。对27例病例的分析显示，PSA似乎比PAP更敏感，因为17例前列腺癌对PSA呈阳性反应，而其中只有3例对PAP呈阴性反应。大多数高分化腺型前列腺癌呈强阳性反应。然而，低分化实体癌仅呈轻度阳性反应。所有对照以及膀胱癌和肾癌对PAP或PSA均呈阴性反应。
