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Isotretinoin, acne, and Crohn's disease: a convergence of bad skin, bad science, and bad litigation creates the perfect storm.

出版信息

Gastroenterol Hepatol (N Y). 2013 Nov;9(11):752-5.

PMID:24764796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3995201/
Abstract
摘要

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Isotretinoin, acne, and Crohn's disease: a convergence of bad skin, bad science, and bad litigation creates the perfect storm.异维A酸、痤疮与克罗恩病:糟糕的皮肤状况、糟糕的科学研究以及糟糕的诉讼交织在一起,引发了一场完美风暴。
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Compliance with national guidelines on isotretinoin: where are we 2 years since the last audit? Results of the National Isotretinoin Re-Audit 2014.异维A酸国家指南的遵循情况:自上次审核以来的两年我们处于什么状况?2014年全国异维A酸再审核结果
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Treatment of severe acne with isotretinoin in patients with inflammatory bowel disease.异维A酸治疗炎症性肠病患者的重度痤疮
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The effect of systemic isotretinoin treatment on skin biophysicalparameters among patients with acne vulgaris.异维 A 酸系统治疗对寻常痤疮患者皮肤生物物理参数的影响。
Turk J Med Sci. 2016 Dec 20;46(6):1641-1644. doi: 10.3906/sag-1507-31.
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J Am Acad Dermatol. 2021 Jan;84(1):228-229. doi: 10.1016/j.jaad.2020.07.041. Epub 2020 Jul 17.
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The effect of continuous high versus low dose oral isotretinoin regimens on dermcidin expression in patients with moderate to severe acne vulgaris.连续高剂量与低剂量口服异维 A 酸方案对中重度寻常痤疮患者皮肤防御素表达的影响。
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A propensity score matched cohort study identifying an association of acne, but not oral antibiotic or isotretinoin use, with risk of incident inflammatory bowel disease.一项倾向评分匹配队列研究表明,痤疮与炎症性肠病发病风险相关,而口服抗生素或异维 A 酸的使用与该风险无关。
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本文引用的文献

1
Evidence on acne therapy.痤疮治疗的证据。
Sao Paulo Med J. 2013;131(3):193-7. doi: 10.1590/1516-3180.2013.1313616.
2
Alleged isotretinoin-associated inflammatory bowel disease: disproportionate reporting by attorneys to the Food and Drug Administration Adverse Event Reporting System.疑似异维 A 酸相关性炎症性肠病:律师向食品和药物管理局不良事件报告系统的不当报告。
J Am Acad Dermatol. 2013 Sep;69(3):393-8. doi: 10.1016/j.jaad.2013.04.031. Epub 2013 May 14.
3
The weight of evidence on the association of isotretinoin use and the development of inflammatory bowel disease.关于异维A酸使用与炎症性肠病发生之间关联的证据权重。
JAMA Dermatol. 2013 Feb;149(2):221-2. doi: 10.1001/jamadermatol.2013.1348.
4
Isotretinoin and risk for inflammatory bowel disease: a nested case-control study and meta-analysis of published and unpublished data.异维 A 酸与炎症性肠病风险:基于已发表和未发表数据的巢式病例对照研究和荟萃分析。
JAMA Dermatol. 2013 Feb;149(2):216-20. doi: 10.1001/jamadermatol.2013.1344.
5
Isotretinoin use and the risk of inflammatory bowel disease: a population-based cohort study.异维 A 酸的使用与炎症性肠病风险:基于人群的队列研究。
J Invest Dermatol. 2013 Apr;133(4):907-12. doi: 10.1038/jid.2012.387. Epub 2012 Oct 25.
6
High-dose isotretinoin in acne vulgaris: improved treatment outcomes and quality of life.寻常痤疮给予大剂量异维 A 酸治疗:改善治疗结局和生活质量。
Int J Dermatol. 2012 Sep;51(9):1123-30. doi: 10.1111/j.1365-4632.2011.05409.x.
7
Effects of isotretinoin treatment on general psychiatric symptoms, quality of life and social phobia in acne vulgaris patients.异维A酸治疗对寻常痤疮患者一般精神症状、生活质量及社交恐惧症的影响。
J Eur Acad Dermatol Venereol. 2013 Feb;27(2):260-1. doi: 10.1111/j.1468-3083.2011.04439.x. Epub 2012 Jan 9.
8
Isotretinoin use and the risk of inflammatory bowel disease.异维A酸的使用与炎症性肠病风险
Am J Gastroenterol. 2011 May;106(5):1000-2; author reply 1002-3. doi: 10.1038/ajg.2011.28.
9
A prospective trial of the effects of isotretinoin on quality of life and depressive symptoms.前瞻性研究异维 A 酸对生活质量和抑郁症状的影响。
Br J Dermatol. 2010 Dec;163(6):1323-9. doi: 10.1111/j.1365-2133.2010.10060.x.
10
Effectiveness of conventional, low-dose and intermittent oral isotretinoin in the treatment of acne: a randomized, controlled comparative study.传统低剂量和间歇性口服异维 A 酸治疗痤疮的疗效:一项随机对照比较研究。
Br J Dermatol. 2011 Jun;164(6):1369-75. doi: 10.1111/j.1365-2133.2010.10152.x. Epub 2011 May 17.