Costa Caroline Sousa, Bagatin Edileia
Universidade Federal de São Paulo, Brazil.
Sao Paulo Med J. 2013;131(3):193-7. doi: 10.1590/1516-3180.2013.1313616.
Among the current treatments available for acne vulgaris, many widely practiced options lack support from studies at the best level of scientific evidence. The aim of this narrative review was to present the very latest information on topical and systemic treatments for acne vulgaris. Information from systematic reviews and well-designed clinical trials, obtained through a systematic search of the major medical databases, is emphasized. There are important issues regarding the clinical management of acne that still lack consistent grounding in scientific evidence. Among these are the optimum dose and duration of treatment with oral antibiotics that can be given without inducing bacterial resistance, and the safety of oral isotretinoin.
在目前可用于寻常痤疮的治疗方法中，许多广泛应用的方法缺乏最高科学证据水平研究的支持。本叙述性综述的目的是介绍寻常痤疮局部和全身治疗的最新信息。强调通过系统检索主要医学数据库获得的系统评价和精心设计的临床试验信息。关于痤疮临床管理的重要问题在科学证据方面仍缺乏一致的依据。其中包括在不诱导细菌耐药性的情况下口服抗生素治疗的最佳剂量和疗程，以及口服异维甲酸的安全性。
