Kumar Sunil, Gupta Amit, Diwan Sanjay K, Bhake Arvind
Department of Medicine.
Department of Pathology, Jawahar Lal Nehru Medical College, DMIMS, Sawangi, Wardha, India.
Clin Pract. 2012 Jun 7;2(3):e62. doi: 10.4081/cp.2012.e62. eCollection 2012 May 29.
Subcutaneous swelling as first clinical presentation of small cell lung carcinoma is uncommon and rarely reported in literature. This case highlights a rare presentation in which subcutaneous swelling was the first clinical manifestation of a small cell carcinoma of lung which also had metastasis to rib bone, muscle and pleural involvement as pleural effusion. We describe the case of a 64-year-old male patient who presented with dyspnea, pleuritic pain, loss of weight and nodule on his anterior chest, back and left arm suspicious of lipoma. Biopsies revealed small cell carcinoma of lung. This case demonstrates the meticulous work up of subcutaneous swelling in the clinical scenario of breathlessness, chest pain and loss of weight.
皮下肿胀作为小细胞肺癌的首发临床表现并不常见，文献中鲜有报道。本病例突出了一种罕见的表现，即皮下肿胀是肺癌小细胞癌的首发临床表现，该病例还伴有肋骨、肌肉转移以及胸腔积液导致的胸膜受累。我们描述了一名64岁男性患者的病例，该患者出现呼吸困难、胸膜炎性疼痛、体重减轻，前胸、后背和左臂有可疑脂肪瘤样结节。活检显示为肺癌小细胞癌。本病例展示了在呼吸困难、胸痛和体重减轻的临床情况下，对皮下肿胀进行细致检查的过程。
