Leonard Maeve M, Nekolaichuk Cheryl, Meagher David J, Barnes Christopher, Gaudreau Jean-David, Watanabe Sharon, Agar Meera, Bush Shirley H, Lawlor Peter G
University of Limerick, Limerick, Ireland.
Division of Palliative Care Medicine, Department of Oncology, University of Alberta, Alberta, Canada; Tertiary Palliative Care Unit, Covenant Health, Grey Nuns Hospital, Edmonton, Alberta, Canada.
J Pain Symptom Manage. 2014 Aug;48(2):176-90. doi: 10.1016/j.jpainsymman.2013.10.024. Epub 2014 Apr 21.
Delirium is a common, distressing neuropsychiatric complication for patients in palliative care settings, where the need to minimize burden yet accurately assess delirium is hugely challenging.
This review focused on the optimal clinical and research application of delirium assessment tools and methods in palliative care settings.
In addition to multidisciplinary input from delirium researchers and other relevant stakeholders at an international meeting, we searched PubMed (1990-2012) and relevant reference lists to identify delirium assessment tools used either exclusively or partly in the context of palliative care.
Of the 26 delirium scales identified, we selected six for in-depth review: three screening tools, two severity measures, and one research tool for neuropsychological assessment of delirium. These tools differed regarding intended use, ease of use, training requirements, psychometric properties, and validation in or suitability for palliative care populations. The Nursing Delirium Screening Scale, Single Question in Delirium, or Confusion Assessment Method, ideally with a brief attention test, can effectively screen for delirium. Favoring inclusivity, use of Diagnostic and Statistical Manual of Mental Disorders-IV criteria gives the best results for delirium diagnosis. The Revised Delirium Rating Scale and the Memorial Delirium Assessment Scale are the best available options for monitoring severity, and the Cognitive Test for Delirium provides detailed neuropsychological assessment for research purposes.
Given the unique characteristics of patients in palliative care settings, further contextually sensitive studies of delirium assessment are required in this population.
谵妄是姑息治疗环境中患者常见且令人痛苦的神经精神并发症,在这种情况下,既要尽量减轻负担又要准确评估谵妄极具挑战性。
本综述聚焦于谵妄评估工具和方法在姑息治疗环境中的最佳临床及研究应用。
除了在一次国际会议上谵妄研究人员和其他相关利益攸关方提供的多学科意见外,我们检索了PubMed(1990 - 2012年)及相关参考文献列表,以确定专门或部分用于姑息治疗背景下的谵妄评估工具。
在确定的26种谵妄量表中,我们选择了6种进行深入综述:三种筛查工具、两种严重程度测量工具以及一种用于谵妄神经心理学评估的研究工具。这些工具在预期用途、易用性、培训要求、心理测量特性以及在姑息治疗人群中的验证或适用性方面存在差异。护理谵妄筛查量表、谵妄单问题或混乱评估方法,理想情况下结合简短注意力测试,可有效筛查谵妄。采用《精神疾病诊断与统计手册》第四版标准以保证包容性,在谵妄诊断方面效果最佳。修订版谵妄评定量表和纪念谵妄评估量表是监测严重程度的最佳可用选项,谵妄认知测试为研究目的提供详细的神经心理学评估。
鉴于姑息治疗环境中患者的独特特征,该人群需要进一步开展针对谵妄评估的情境敏感性研究。