多形性腺瘤和腮腺良性肿瘤：包膜外剥离术与腮腺浅叶切除术——文献综述与荟萃分析
Pleomorphic adenoma and benign parotid tumors: extracapsular dissection vs superficial parotidectomy--review of literature and meta-analysis.
作者信息
Foresta Enrico, Torroni Andrea, Di Nardo Francesco, de Waure Chiara, Poscia Andrea, Gasparini Giulio, Marianetti Tito Matteo, Pelo Sandro
机构信息
Maxillo-Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
Maxillo-Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Jun;117(6):663-76. doi: 10.1016/j.oooo.2014.02.026. Epub 2014 Mar 12.
OBJECTIVE
This study compared extracapsular dissection (ED) vs superficial parotidectomy (SP) in the treatment of pleomorphic adenoma and benign parotid tumors.
STUDY DESIGN
The research covered the years 1950-2011 in PubMed, Ovid MEDLINE, the Cochrane Database of Systematic Reviews, and Scopus. Of 1152 articles screened, 123 studies met the inclusion criteria. A review of the nomenclature of the different parotid surgery techniques was done. Recurrence rate, permanent facial nerve paralysis, and Frey syndrome of patients who underwent ED vs those who underwent SP were compared by meta-analysis.
RESULTS
Our meta-analysis data comparing ED and SP found that: (1) the recurrence rate is higher in patients treated with SP; (2) SP has a higher incidence of cranial nerve VII paralysis; and (3) Frey syndrome is more common after SP.
CONCLUSIONS
ED may be a viable option in the treatment of unilateral benign parotid tumors of the superficial lobe, sized less than 4 cm, without involvement of the facial nerve.
目的
本研究比较了在多形性腺瘤和腮腺良性肿瘤治疗中囊外剥离术（ED）与腮腺浅叶切除术（SP）的效果。
研究设计
检索了1950年至2011年期间PubMed、Ovid MEDLINE、Cochrane系统评价数据库和Scopus中的文献。在筛选的1152篇文章中，有123项研究符合纳入标准。对不同腮腺手术技术的命名进行了回顾。通过荟萃分析比较了接受ED与接受SP的患者的复发率、永久性面神经麻痹和味觉出汗综合征。
结果
我们比较ED和SP的荟萃分析数据发现：（1）接受SP治疗的患者复发率更高；（2）SP导致面神经VII麻痹的发生率更高；（3）SP术后味觉出汗综合征更常见。
结论
对于直径小于4 cm、未累及面神经的单侧腮腺浅叶良性肿瘤，ED可能是一种可行的治疗选择。
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