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进行性系统性硬化症患者的外分泌胰腺功能

Exocrine pancreatic function in patients with progressive systemic sclerosis.

作者信息

Hendel L, Worning H

机构信息

Dept. of Dermatology, University of Copenhagen, Rigshospitalet, Denmark.

出版信息

Scand J Gastroenterol. 1989 May;24(4):461-6. doi: 10.3109/00365528909093075.

DOI:10.3109/00365528909093075
PMID:2476844
Abstract

The exocrine pancreatic function was investigated in 16 patients with progressive systemic sclerosis by means of a meal test (Lundh test) and in 9 of the patients by the secretin-cholecystokinin test as well. Gastrointestinal involvement with progressive systemic sclerosis was evaluated by esophageal manometry and by routine roentgenographic series of the small bowel. Fecal fat excretion measurement, the D-xylose absorption test, and a small-intestinal biopsy procedure were carried out. Duodenal juice was cultured and bacterial counts were estimated. One-third of the patients had reduced exocrine pancreatic function, but only four patients had unequivocally a reduction that could be of clinical importance. The results obtained with the meal test were in accordance with the secretin-cholecystokinin test, indicating a preserved capacity for endogenous stimulation.

摘要

通过进餐试验(伦德试验)对16例进行性系统性硬化症患者的胰腺外分泌功能进行了研究,其中9例患者还进行了促胰液素-缩胆囊素试验。通过食管测压和小肠常规X线系列检查评估进行性系统性硬化症患者的胃肠道受累情况。进行了粪便脂肪排泄测量、D-木糖吸收试验和小肠活检。对十二指肠液进行培养并估计细菌计数。三分之一的患者胰腺外分泌功能降低,但只有4例患者的降低具有明确的临床意义。进餐试验的结果与促胰液素-缩胆囊素试验结果一致,表明内源性刺激能力保留。

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1
Exocrine pancreatic function in patients with progressive systemic sclerosis.进行性系统性硬化症患者的外分泌胰腺功能
Scand J Gastroenterol. 1989 May;24(4):461-6. doi: 10.3109/00365528909093075.
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Pancreatic enzymes in human duodenal juice--a comparison of responses in secretin pancreozymin and Lundh Borgström tests.人十二指肠液中的胰酶——促胰液素-促胰酶素试验与伦德-博斯特罗姆试验反应的比较
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Secretin-pancreozymin test with synthetic secretin and cholecystokinin octapeptide.使用合成促胰液素和胆囊收缩素八肽进行促胰液素-促胰酶素试验。
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引用本文的文献

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The PREdictor of MAlnutrition in Systemic Sclerosis (PREMASS) Score: A Combined Index to Predict 12 Months Onset of Malnutrition in Systemic Sclerosis.系统性硬化症营养不良预测(PREMASS)评分:预测系统性硬化症12个月内营养不良发病的综合指标。
Front Med (Lausanne). 2021 Mar 17;8:651748. doi: 10.3389/fmed.2021.651748. eCollection 2021.
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Exocrine pancreatic function is preserved in systemic sclerosis.系统性硬化症患者的外分泌胰腺功能得以保留。
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Gastrointestinal Manifestations of Systemic Sclerosis.
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Rheumatology (Sunnyvale). 2018;8(1). doi: 10.4172/2161-1149.1000235. Epub 2018 Mar 30.
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Chronic calcifying pancreatitis in rheumatic diseases.风湿性疾病中的慢性钙化性胰腺炎。
Ann Rheum Dis. 1995 Jan;54(1):77-8. doi: 10.1136/ard.54.1.77.
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Clinical aspects of systemic sclerosis (scleroderma).系统性硬化症(硬皮病)的临床方面
Ann Rheum Dis. 1991 Nov;50 Suppl 4(Suppl 4):854-61. doi: 10.1136/ard.50.suppl_4.854.
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Dietary intake and nutritional status in patients with systemic sclerosis.系统性硬化症患者的饮食摄入与营养状况
Ann Rheum Dis. 1992 Oct;51(10):1143-8. doi: 10.1136/ard.51.10.1143.
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Gastrointestinal transit times of radiolabeled meal in progressive systemic sclerosis.
Dig Dis Sci. 1992 Sep;37(9):1404-8. doi: 10.1007/BF01296011.