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人十二指肠液中的胰酶——促胰液素-促胰酶素试验与伦德-博斯特罗姆试验反应的比较

Pancreatic enzymes in human duodenal juice--a comparison of responses in secretin pancreozymin and Lundh Borgström tests.

作者信息

Braganza J M, Herman K, Hine P, Kay G, Sandle G I

出版信息

Gut. 1978 May;19(5):358-66. doi: 10.1136/gut.19.5.358.

Abstract

We have compared the concentrations and total outputs of trypsin, amylase, and lipase secreted into the duodenum during secretin pancreozymin and Lundh Borgström tests in order to assess the relative intensity of pancreatic stimulation provided by these means. The mean concentration of trypsin, and the mean 10 minute total output of trypsin, amylase, and lipase after the meal (though less than the peak post-prandial responses) were equal to the respective peak enzyme responses after intravenous injection of 2 Crick Harper Raper units per kg of secretin Boots; and after intravenous injection of 2 Crick Harper Raper units per kg of pancreozymin Boots.

摘要

我们比较了在促胰液素-缩胆囊素试验和伦德-博斯特罗姆试验期间分泌到十二指肠中的胰蛋白酶、淀粉酶和脂肪酶的浓度及总分泌量,以评估这些方法所提供的胰腺刺激的相对强度。餐后胰蛋白酶的平均浓度以及胰蛋白酶、淀粉酶和脂肪酶的平均10分钟总分泌量(尽管低于餐后峰值反应)与静脉注射每千克体重2个克里克-哈珀-雷珀单位促胰液素(博姿公司生产)后以及静脉注射每千克体重2个克里克-哈珀-雷珀单位缩胆囊素(博姿公司生产)后的相应酶峰值反应相当。

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Experiments with cholecystokinin.胆囊收缩素实验
Acta Radiol (Stockh). 1961 Mar;55:193-206. doi: 10.3109/00016926109174540.
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Purification of hog pancreatic lipase.猪胰脂肪酶的纯化
Arch Biochem Biophys. 1959 Jul;83(1):309-19. doi: 10.1016/0003-9861(59)90036-0.
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Enhancement of pancreatic enzyme synthesis by pancreozymin.促胰液素对胰腺酶合成的增强作用。
Am J Physiol. 1967 Jul;213(1):215-8. doi: 10.1152/ajplegacy.1967.213.1.215.

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