*German Center for Vertigo and Balance Disorders, †Department of Otorhinolaryngology - Head and Neck Surgery, and ‡Institute of Clinical Radiology, Grosshadern Medical Center, University of Munich, Munich, Germany.
Otol Neurotol. 2014 Jun;35(5):880-3. doi: 10.1097/MAO.0000000000000393.
To visualize the progression of endolymphatic hydrops in a patient with Ménière's disease.
A 53-year-old patient with definite Ménière's disease underwent locally enhanced inner ear magnetic resonance imaging (LEIM) for visualizing endolymphatic hydrops. Two years later, a second magnetic resonance imaging was performed for follow-up.
The first magnetic resonance image confirmed the presence of endolymphatic hydrops and a treatment with betahistine was begun. Two years later, no more vertigo attacks occurred. The audiometry showed a deterioration of the hearing loss on both sides, whereas the caloric irrigation revealed normal results on both occasions. In comparison to the first examination, the second LEIM showed an augmented endolymphatic hydrops in both the cochlear and the vestibular compartments.
For the first time, this case of Ménière's disease shows an enlargement of endolymphatic hydrops in 1 individual in the course of 2 years. A further development of the LEIM technique is desirable to enable the volumetric quantification of endolymphatic hydrops and to monitor the effect of therapies on the course of Ménière's disease.
可视化梅尼埃病患者内淋巴积水的进展。
一名 53 岁的明确梅尼埃病患者接受局部增强内耳磁共振成像（LEIM）以可视化内淋巴积水。两年后，进行了第二次磁共振成像以进行随访。
第一次磁共振成像证实存在内淋巴积水，并开始使用倍他司汀进行治疗。两年后，不再发生眩晕发作。听力测试显示双侧听力损失恶化，而冷热激发试验两次均显示正常结果。与第一次检查相比，第二次 LEIM 显示双侧耳蜗和前庭腔的内淋巴积水均增加。
首例梅尼埃病病例在 2 年内显示出内淋巴积水在 1 名个体中的增大。进一步发展 LEIM 技术以实现内淋巴积水的定量评估并监测治疗对梅尼埃病病程的影响是可取的。
