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膜迷路疝入水平半规管与梅尼埃病的冷热反应受损相关。

Herniation of the membranous labyrinth into the horizontal semicircular canal is correlated with impaired caloric response in Ménière's disease.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Integrated Centre for Balance Disorders, University of Munich, Munich, Germany.

出版信息

Otol Neurotol. 2012 Oct;33(8):1375-9. doi: 10.1097/MAO.0b013e318268d087.

DOI:10.1097/MAO.0b013e318268d087
PMID:22918115
Abstract

INTRODUCTION

Canal paresis of the horizontal semicircular canal in Ménière's disease is a frequent finding. Endolymphatic hydrops is the single most characteristic morphologic finding in Ménière's disease. However, the relationship between endolymphatic hydrops and canal paresis is still not elucidated.

METHODS

We used magnetic resonance imaging to visualize herniation of parts of the vestibular membranous labyrinth into the horizontal semicircular canal and correlated this morphologic feature with the caloric function of the horizontal semicircular canal.

RESULTS

Patients who showed herniation into the horizontal canal had a significantly impaired caloric function when compared with patients without this morphologic feature.

CONCLUSION

Herniation into the semicircular canal may be the morphologic correlate for impaired caloric response in patients with Ménière's disease.

摘要

引言

梅尼埃病中水平半规管的管腔运动功能减退较为常见。内淋巴积水是梅尼埃病最具特征性的形态学表现。然而,内淋巴积水和管腔运动功能减退之间的关系尚未阐明。

方法

我们使用磁共振成像观察到部分前庭膜迷路疝入水平半规管,并将这种形态特征与水平半规管的冷热功能相关联。

结果

与没有这种形态特征的患者相比,出现水平半规管疝入的患者冷热功能明显受损。

结论

疝入半规管可能是梅尼埃病患者冷热反应受损的形态学相关因素。

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