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诊断病例。厚皮性多指(趾)症。

Case for diagnosis. Pachydermodactyly.

作者信息

Requena Camila Bueno, Miot Hélio Amante, Marques Mariângela Esther Alencar, Miot Luciane Donida Bartoli

机构信息

Paulista State University Júlio de Mesquita Filho, UNESP, Botucatu, SP, Brazil.

出版信息

An Bras Dermatol. 2014 Mar-Apr;89(2):359-60. doi: 10.1590/abd1806-4841.20142689.

DOI:10.1590/abd1806-4841.20142689
PMID:24770524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4008078/
Abstract

Pachydermodactyly is a rare and benign form of acquired digital fibromatosis characterized by the expansion of soft tissue around proximal phalanges and interphalangeal joints. The etiology remains unknown, although it is suggested that repetitive mechanic trauma like the interlacing or rubbing of the fingers can lead to skin thickening. We report a case of a young man with skin thickening around interphalangeal joints and compulsive finger manipulation habit. The histopathology disclosed hyperkeratosis, discrete papillomatosis, mild increase of fibroblasts and dermal mucinosis. The lesions regressed partially, after finger manipulation was stopped.

摘要

厚皮性多指(趾)畸形是一种罕见的后天性指(趾)纤维瘤病良性形式,其特征为近端指(趾)骨和指间关节周围软组织增生。病因尚不清楚,不过有人认为,诸如手指交叉或摩擦等重复性机械性创伤可导致皮肤增厚。我们报告一例年轻男性病例,其指间关节周围皮肤增厚且有强迫性手指操作习惯。组织病理学显示有角化过度、散在性乳头瘤病、成纤维细胞轻度增多和真皮粘蛋白沉积症。停止手指操作后,病变部分消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/4f2ab5460da0/abd-89-02-0359-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/187f097f3faf/abd-89-02-0359-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/5de255e8eab6/abd-89-02-0359-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/4f2ab5460da0/abd-89-02-0359-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/187f097f3faf/abd-89-02-0359-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/5de255e8eab6/abd-89-02-0359-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff5/4008078/4f2ab5460da0/abd-89-02-0359-g03.jpg

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本文引用的文献

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Factitious disorders of the upper extremity.上肢做作性障碍。
J Am Acad Orthop Surg. 2012 Feb;20(2):78-85. doi: 10.5435/JAAOS-20-02-078.
2
Pachydermodactyly: an uncommon acquired digital fibromatosis.厚皮性指端纤维瘤病:一种罕见的后天性指端纤维瘤病。
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Pachydermodactyly.厚皮性指节垫
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Pachydermodactyly - A Case Report and Review of Literature.厚皮性指节垫——病例报告及文献综述
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Pachydermodactyly with Broder Hand Span and Long Fingers: A Case Report.伴有布罗德手跨度和长手指的厚皮性多指(趾)畸形:一例报告
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Pachydermodactyly - a report of two cases.厚皮性指节垫——两例报告
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Pachydermodactyly: a review.厚皮性指节垫:综述
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Pachydermodactyly in a young girl: cutaneous manifestation of a psychiatric disorder?一名年轻女孩的厚皮性指端皮炎:一种精神障碍的皮肤表现?
Pediatr Dermatol. 2010 May-Jun;27(3):306-8. doi: 10.1111/j.1525-1470.2010.01146.x.
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Transgrediens pachydermodactyly: report of a case.进行性厚皮性皮病甲:一例报告
An Bras Dermatol. 2009 Mar-Apr;84(2):190-3. doi: 10.1590/s0365-05962009000200014.
6
A case of deforming pachydermodactyly.一例变形性厚皮性指端皮炎。
J Clin Rheumatol. 2009 Mar;15(2):78-80. doi: 10.1097/RHU.0b013e31819b87cd.
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Pachydermodactyly: case report and review of the literature.厚皮性多指(趾)畸形:病例报告及文献综述
J Cutan Med Surg. 2007 Sep-Oct;11(5):185-7. doi: 10.2310/7750.2007.00024.
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Pachydermodactyly: four additional cases.厚皮指:另外4例病例
Clin Rheumatol. 2007 Jun;26(6):962-4. doi: 10.1007/s10067-006-0210-9. Epub 2006 Mar 22.
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Pachydermodactyly: reflecting obsessive-compulsive behavior?厚皮性多指(趾)畸形:反映强迫行为?
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