Santos Guida, Sousa Lourdes
Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, EPE, Lisbon, Portugal.
An Bras Dermatol. 2014 Mar-Apr;89(2):361-2. doi: 10.1590/abd1806-4841.20142403.
Multiple autoimmune syndrome is a rare condition, described by Humbert and Dupond in 1988. It is defined by the association of at least 3 autoimmune diseases in the same patient. Vitiligo is the most common skin condition in this syndrome. This article presents the case of a 31-year-old male with vitiligo, alopecia areata, Crohn's disease, psoriasis vulgaris and oral lichen planus. The rarity of this case is highlighted by the coexistence of four autoimmune skin diseases in association with Crohn's disease, never described in the literature.
多发性自身免疫综合征是一种罕见疾病，由洪伯特和迪蓬于1988年描述。它被定义为同一患者中至少3种自身免疫性疾病的关联。白癜风是该综合征中最常见的皮肤疾病。本文介绍了一名31岁男性的病例，该患者患有白癜风、斑秃、克罗恩病、寻常型银屑病和口腔扁平苔藓。该病例的罕见之处在于四种自身免疫性皮肤病与克罗恩病并存，这在文献中从未有过描述。
