Safren Steven A, Thomas Beena E, Mayer Kenneth H, Biello Katie B, Mani Jamuna, Rajagandhi Vijaylakshmi, Periyasamy Murugesan, Swaminathan Soumya, Mimiaga Matthew J
Behavioral Medicine, Harvard Medical School/Massachusetts General Hospital, 1 Bowdoin Sq, 7th Floor, Boston, MA, USA,
AIDS Behav. 2014 Oct;18(10):1904-12. doi: 10.1007/s10461-014-0773-4.
This is a 2-arm pilot randomized controlled trial (N = 96) of a behavioral intervention (4 group and 4 individual sessions) integrating risk reduction counseling with counseling to foster self-acceptance in MSM in India compared to enhanced standard of care (ESOC). Both conditions involved HIV and STI testing and counseling at baseline and 6-months, and assessments of condomless sex at baseline, 3-, and 6-months. A significant condition by time interaction suggested a difference in the rate of change in number of anal sex acts without condoms in the intervention versus ESOC (p < 0.0001). Post hoc contrasts suggested that the overall difference was due to intervention-response at 3-months. The incidence of bacterial STIs was 17.5 % in the intervention condition and a 28.6 % in ESOC. Addressing self-acceptance and related psychosocial concerns in the context sexual risk reduction counseling for MSM in India was feasible and acceptable. Testing the intervention for efficacy is justified.
这是一项双臂试点随机对照试验（N = 96），对比强化标准护理（ESOC），对印度男男性行为者（MSM）开展一项行为干预（4次小组和4次个人辅导课程），该干预将降低风险咨询与促进自我接纳的咨询相结合。两种情况均包括在基线和6个月时进行艾滋病毒和性传播感染检测及咨询，并在基线、3个月和6个月时评估无保护性行为。显著的条件与时间交互作用表明，干预组与ESOC组在无保护肛交行为数量的变化率上存在差异（p < 0.0001）。事后对比表明，总体差异是由于3个月时的干预反应。干预组细菌性性传播感染的发生率为17.5%，ESOC组为28.6%。在印度针对男男性行为者的性风险降低咨询中解决自我接纳及相关心理社会问题是可行且可接受的。对该干预措施进行疗效测试是合理的。
