Gershuni D H, Skyhar M J, Danzig L A, Camp J, Hargens A R, Akeson W H
Division of Orthopaedics and Rehabilitation, Veterans Administration Medical Center, San Diego, California 92161.
J Bone Joint Surg Am. 1989 Oct;71(9):1363-70.
Longitudinal tears were created in canine lateral menisci and techniques were applied to induce healing by removal of a core of tissue from the periphery of the meniscus to the tear or by implantation of a vascularized synovial flap into the tear. The meniscal tears did not heal in knees that were not immobilized, and they healed poorly and sporadically in knees that were immobilized in a cast but bore some weight. However, a higher percentage of tears that were treated by the core-removal or synovial-flap technique healed when the knee was firmly immobilized and weight-bearing was prevented by the use of an external skeletal fixator across the joint for eight to twelve weeks. Neovascularization and access to a source of reparative cells appear to be important in the healing process.
在犬类外侧半月板制造纵向撕裂，并应用技术通过从半月板周边向撕裂处去除组织核心或通过将带血管的滑膜瓣植入撕裂处来诱导愈合。在未固定的膝关节中，半月板撕裂未愈合，而在用石膏固定但承受一定重量的膝关节中，愈合情况较差且不规律。然而，当膝关节通过在关节上使用外部骨外固定器牢固固定并防止负重八至十二周时，采用去除组织核心或滑膜瓣技术治疗的撕裂愈合的比例更高。新生血管形成和获得修复细胞来源在愈合过程中似乎很重要。
