Coniglio M A, Faro G, Giammanco G, Pignato S, Marranzano M
J Prev Med Hyg. 2013 Dec;54(4):223-6.
The purpose of this study was to investigate the antibacterial effect of 71 locally produced honeys from different botanical sources collected from apiarist's open markets in Sicily.
Antimicrobial activity was determined against Escherichia coli (ATCC 25922) and Salmonella serovar Infantis (ATCC 1523) by an agar-diffusion assay from the estimation of the diameter of the inhibition zone produced by the honeys. Statistically) significant differences (P < .000) regarding inhibition were observed for the honeys tested.
The chestnut and polyfloral honey samples exhibited the largest and highest inhibition (diameter of the inhibition zone > 25 mm) against both E. coli and S. Infantis. The honey of oregano origin showed intermediate or low activity against E. coli and S. Infantis, respectively. Prickly pear and erica honeys showed no antimicrobial activity against the two reference strains.
The results may partially suggest the usefulness of the Sicilian honeys on treating multi-resistant enterobacteria. In light of the enormous potential for application of honey in the clinical practice, it is important that research continues not only into those honeys well recognized as antimicrobial, but also into other locally produced and yet untested honeys.
本研究旨在调查从西西里岛养蜂人露天市场收集的71种不同植物来源的本地蜂蜜的抗菌效果。
通过琼脂扩散试验，根据蜂蜜产生的抑菌圈直径评估其对大肠杆菌（ATCC 25922）和婴儿沙门氏菌（ATCC 1523）的抗菌活性。在测试的蜂蜜中观察到抑菌方面具有统计学显著差异（P <.000）。
栗树蜂蜜和多花蜂蜜样本对大肠杆菌和婴儿沙门氏菌均表现出最大且最高的抑菌效果（抑菌圈直径> 25毫米）。牛至来源的蜂蜜对大肠杆菌和婴儿沙门氏菌分别表现出中等或低活性。仙人掌蜂蜜和欧石南蜂蜜对两种参考菌株均无抗菌活性。
结果可能部分表明西西里蜂蜜在治疗多重耐药性肠杆菌方面的有用性。鉴于蜂蜜在临床实践中的巨大应用潜力，不仅要继续研究那些公认为具有抗菌性的蜂蜜，还要研究其他本地生产但尚未测试的蜂蜜，这一点很重要。
