a Department of Pharmaceutical Toxicology , Faculty of Pharmacy, Istanbul University , Istanbul , Turkey.
Food Addit Contam Part B Surveill. 2013;6(4):265-9. doi: 10.1080/19393210.2013.814719. Epub 2013 Jul 18.
Ochratoxin A (OTA) is a naturally occurring mycotoxin and widespread food contaminant which results in a probable human exposure. A total of 85 samples (50 dried grapes, 10 grape juices and 25 pekmez (boiled and concentrated grape juices) were collected from different supermarkets and traditional bazaars in Istanbul during 2008-2009. An analytical method based on immuno-affinity column for clean-up and high-performance liquid chromatography equipped with fluorescence detection was used to determine the OTA. Contamination frequencies were 8%, 20% and 88% with mean concentrations of positive samples of 1.15, 1.40 and 2.04 µg/kg for dried grapes, grape juices and pekmez samples, respectively. These levels were lower than the maximum levels as set by the European Commission (EC). However, 12 of 25 pekmez samples had higher levels than permitted by the European Union (EU) for safe consumption.
赭曲霉毒素 A（OTA）是一种天然存在的真菌毒素，广泛存在于污染的食物中，可能会导致人类暴露。在 2008 年至 2009 年期间，从伊斯坦布尔的不同超市和传统集市共采集了 85 份样本（50 份葡萄干、10 份葡萄汁和 25 份蜜饯（煮沸浓缩的葡萄汁）。采用基于免疫亲和柱净化和高效液相色谱-荧光检测的分析方法来测定 OTA。污染频率分别为 8%、20%和 88%，阳性样本的平均浓度分别为 1.15、1.40 和 2.04μg/kg，用于葡萄干、葡萄汁和蜜饯样品。这些水平低于欧盟委员会（EC）设定的最大限量。然而，25 份蜜饯样品中有 12 份的水平高于欧盟规定的安全食用限量。
