Senger E, Menzel I, Holzmann H
Abteilung I des Zentrums der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität, Frankfurt/Main.
Derm Beruf Umwelt. 1989 Sep-Oct;37(5):167-70.
Reactions induced by neurotoxic effects with lindane (gamma-hexachlorcyclohexane) after treatment of infants have been reported by different authors. This has led to controversial discussions as to the indication for therapy with lindane in early infancy. To our knowledge there are to date no published reports on the concentration of lindane in mother's milk after local scabies therapy. In a mother treated with lindane for scabies we found elevated levels of lindane in the mother's milk. Compared to average levels of lindane in mother's milk (0.03 ppm, milk-fat) there was a 30-fold increase after three-day treatment and a 66-fold elevation after an additional one-day treatment with lindane. The problems arising and alternative therapy are discussed.
不同作者报道了婴儿使用林丹（γ-六氯环己烷）治疗后出现的神经毒性反应。这引发了关于婴儿早期林丹治疗适应症的争议性讨论。据我们所知，迄今为止尚无关于局部疥疮治疗后母乳中林丹浓度的公开报道。在一名接受林丹治疗疥疮的母亲中，我们发现其母乳中林丹水平升高。与母乳中林丹的平均水平（0.03 ppm，乳脂）相比，三天治疗后增加了30倍，额外一天林丹治疗后升高了66倍。文中讨论了由此产生的问题及替代疗法。
