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用于体内调强放射治疗剂量测定的MOSFET剂量计再利用中的脉冲电流退火方法研究。

Investigation of a pulsed current annealing method in reusing MOSFET dosimeters for in vivo IMRT dosimetry.

作者信息

Luo Guang-Wen, Qi Zhen-Yu, Deng Xiao-Wu, Rosenfeld Anatoly

机构信息

Department of Radiation Oncology, Sun Yat-Sen University Cancer Center and State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China.

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia.

出版信息

Med Phys. 2014 May;41(5):051710. doi: 10.1118/1.4871619.

Abstract

PURPOSE

To explore the feasibility of pulsed current annealing in reusing metal oxide semiconductor field-effect transistor (MOSFET) dosimeters for in vivo intensity modulated radiation therapy (IMRT) dosimetry.

METHODS

Several MOSFETs were irradiated at d(max) using a 6 MV x-ray beam with 5 V on the gate and annealed with zero bias at room temperature. The percentage recovery of threshold voltage shift during multiple irradiation-annealing cycles was evaluated. Key dosimetry characteristics of the annealed MOSFET such as the dosimeter's sensitivity, reproducibility, dose linearity, and linearity of response within the dynamic range were investigated. The initial results of using the annealed MOSFETs for IMRT dosimetry practice were also presented.

RESULTS

More than 95% of threshold voltage shift can be recovered after 24-pulse current continuous annealing in 16 min. The mean sensitivity degradation was found to be 1.28%, ranging from 1.17% to 1.52%, during multiple annealing procedures. Other important characteristics of the annealed MOSFET remained nearly consistent before and after annealing. Our results showed there was no statistically significant difference between the annealed MOSFETs and their control samples in absolute dose measurements for IMRT QA (p = 0.99). The MOSFET measurements agreed with the ion chamber results on an average of 0.16% ± 0.64%.

CONCLUSIONS

Pulsed current annealing provides a practical option for reusing MOSFETs to extend their operational lifetime. The current annealing circuit can be integrated into the reader, making the annealing procedure fully automatic.

摘要

目的

探讨脉冲电流退火在体内调强放射治疗(IMRT)剂量测定中重复使用金属氧化物半导体场效应晶体管(MOSFET)剂量仪的可行性。

方法

使用6 MV X射线束在射野中心轴最大剂量深度(d(max))处对多个MOSFET进行照射,栅极电压为5 V,然后在室温下零偏置退火。评估多次照射 - 退火循环中阈值电压偏移的恢复百分比。研究退火后MOSFET的关键剂量学特性,如剂量仪的灵敏度、重复性、剂量线性以及动态范围内的响应线性。还展示了将退火后的MOSFET用于IMRT剂量测定实践的初步结果。

结果

在16分钟内进行24次脉冲电流连续退火后,超过95%的阈值电压偏移可以恢复。在多次退火过程中,平均灵敏度下降为1.28%,范围在1.17%至1.52%之间。退火后MOSFET的其他重要特性在退火前后几乎保持一致。我们的结果表明,在IMRT质量保证的绝对剂量测量中,退火后的MOSFET与其对照样品之间没有统计学上的显著差异(p = 0.99)。MOSFET测量结果与电离室结果平均相差0.16%±0.64%。

结论

脉冲电流退火为重复使用MOSFET以延长其使用寿命提供了一种切实可行的选择。电流退火电路可集成到读取器中,使退火过程完全自动化。

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